Checkpoint Kinase 1 (CHEK1) (Middle Region) Peptide
CHEK1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
-
- Target See all CHEK1 products
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CHEK1 antibody (Catalog #: ARP32588_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
- Synonyms
- An08g10320 Peptide, AO090003000441 Peptide, CHK1 Peptide, chk1 Peptide, C85740 Peptide, Chk1 Peptide, rad27 Peptide, id:ibd2720 Peptide, zgc:56093 Peptide, CHEK1 Peptide, checkpoint kinase 1 Peptide, serine/threonine-protein kinase chk1 Peptide, serine/threonine-protein kinase Chk1 Peptide, CAMK/CAMKL/CHK1 protein kinase Chk1 Peptide, checkpoint kinase 1 S homeolog Peptide, CHEK1 Peptide, ANI_1_2436074 Peptide, AOR_1_768154 Peptide, PTRG_04183 Peptide, SJAG_01680 Peptide, PAAG_04978 Peptide, MCYG_03290 Peptide, VDBG_03742 Peptide, chek1.S Peptide, Chek1 Peptide, chek1 Peptide
- Background
-
CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.
Alias Symbols: CHK1
Protein Interaction Partner: E2F1,E2F4,ATR,CDC25A,CDC25A,CDC25C,RAD51,RELA,AATF,AKT1,ATM,ATR,BLM,CDC25A,CDC25B,CDC25C,CLSPN,CSNK2B,CUL1,CUL4A,HSP90AA1,MDM4,RAD51,RELA,SMAD4,TLK1,TP53,UBB,XIAP,XRCC6,YWHAG,ATM,ATR,BLM,CDC25A,CDC25B,CDC25C,CDKN1A,CLSPN,CSNK2A1,MCD1,MSH2,PRKDC,SFN,TIMELESS,TP53,TP53BP1,XIAP,XRCC5,XRCC6
Protein Size: 476 - Molecular Weight
- 54 kDa
- Gene ID
- 1111
- NCBI Accession
- NM_001274, NP_001265
- UniProt
- O14757
-
You are here:
