TATA-Binding Protein-Associated Phosphoprotein (DR1) (Middle Region) Peptide
DR1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all DR1 products
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
- Protein Region
- Middle Region
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KKTISPEHVI QALESLGFGS YISEVKEVLQ ECKTVALKRR KASSRLENLG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Dr1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
- Synonyms
- BG:DS00929.3 Peptide, CG4185 Peptide, Dmel\\CG4185 Peptide, Dr1 Peptide, NC2 beta Peptide, Nc2b Peptide, dDr1 Peptide, dNC2 Peptide, wu:fj15f04 Peptide, zgc:152914 Peptide, 1700121L09Rik Peptide, Dr1l Peptide, NC2 Peptide, NC2beta Peptide, NC2-BETA Peptide, Negative Cofactor 2beta Peptide, TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN Peptide, TATA-binding protein-associated phosphoprotein Peptide, putative tata-binding protein-associated phosphoprotein Peptide, down-regulator of transcription 1 Peptide, down-regulator of transcription 1, TBP-binding (negative cofactor 2) Peptide, NC2beta Peptide, ECU11_0730 Peptide, EDI_229030 Peptide, PTRG_08168 Peptide, Smp_160150 Peptide, EBI_26279 Peptide, EBI_23074 Peptide, VDBG_02216 Peptide, dr1 Peptide, Dr1 Peptide, DR1 Peptide
- Background
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The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Dr1 can bind to DNA on its own. It is a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Alias Symbols: 1700121L09Rik, Dr1l, NC2, NC2beta
Protein Size: 176 - Molecular Weight
- 19 kDa
- Gene ID
- 13486
- NCBI Accession
- NM_026106, NP_080382
- UniProt
- Q91WV0
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