Dynein, Light Chain, LC8-Type 1 (DYNLL1) (N-Term) Peptide
DYNLL1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DYNLL1 products
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DYNLL1 antibody (Catalog #: ARP51350_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
- Synonyms
- DLC1 Peptide, DLC8 Peptide, DNCL1 Peptide, DNCLC1 Peptide, LC8 Peptide, LC8a Peptide, PIN Peptide, hdlc1 Peptide, dynll2 Peptide, wu:fd56c09 Peptide, zgc:73406 Peptide, Dlc8 Peptide, Dnclc1 Peptide, Pin Peptide, 8kDLC Peptide, lc8 Peptide, dlc1 Peptide, dlc8 Peptide, lc8a Peptide, dncl1 Peptide, dnclc1 Peptide, dynll1a Peptide, MGC68763 Peptide, CDLC2 Peptide, dynll1 Peptide, dynll1b Peptide, pin Peptide, MGC89636 Peptide, dynein light chain LC8-type 1 Peptide, dynein, light chain, LC8-type 1 Peptide, dynein light chain LC8-type 1 S homeolog Peptide, dynein light chain LC8-type 1 L homeolog Peptide, Dynein light chain 1, cytoplasmic Peptide, DYNLL1 Peptide, dynll1 Peptide, Dynll1 Peptide, dynll1.S Peptide, dynll1.L Peptide, dlc-1 Peptide
- Background
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Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
Alias Symbols: DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, MGC126137, MGC126138, PIN, hdlc1
Protein Interaction Partner: BCAS1,DLGAP1,DLGAP1,DYNLL1,MYO5A,NFKBIA,PAN2,PKIA,PKIB,PKIG,SLC25A10,ACTB,ACTC1,ACTG1,ALDOA,BCAS1,BCL2L11,C14orf1,CA2,CACNB1,CLIP2,CS,DAZ1,DLG4,DLGAP1,DNAJB9,DNM2,DNM3,DNMT1,DYNC1H1,DYNC1I1,DYNLL1,EEF1A1,GAPDH,GLUD1,GLUL,GPHN,GRIN3A,HIP1R,HSPA8,LDHA,MAP1B,MARK3,MAST2,ME2,MTA1,MTR,MYO10,MYO5A,NDUFA4L2,NFKBIA,NOS1,NRF1,NTRK1,NTRK2,NTRK3,PAK1,PAN2,PARD3,PAX6,PFKM,PFKP,PKIA,PKIB,PKIG,POLH,RAB4A,RGS2,SHROOM3,THAP8,TP53BP1,TUBA3C,TUBB,TXNDC17,VIM,ZHX1,ZMYND11,ZNF354A,AMOT,ASF1B,Actb,Actg1,Aldoa,BCAS1,BCL2,BCL2L1,BCL2L11,BMF,Bcl2l11,C14orf1,Cacnb1,Car1,Clip2,DDX3X,DLG2,DLG4,DLGAP1,DNAJB9,DYNC1I1,DYNC1I2,DYNLL1,Dlg4,Dnm2,Dnm3,Dnmt3a,Dync1h1,Dync1i1,EEF1A1,Glud1,Glul,Gphn,Grin2a,Grin3a,LOC499110,Ldha,MYO5A,Map1lc3b,Mast1,Mastl,Mdh1,Mta1,Mtr,Myo10,NDUFA4L2,NEK6,NFKBIA,NRF1,NTRK2,Nos1,PABPC1,PAK1,Pard3,Pfkm,Pfkp,Polh,RGS2,SHANK2,SNCG,Shroom1,THAP8,TP53BP1,TRAF3IP3,TXNDC17,Tuba1a,Tuba1a,Tubb2b,Ube2k,Vim,ZHX1
Protein Size: 89 - Molecular Weight
- 10 kDa
- Gene ID
- 8655
- NCBI Accession
- NM_001037494, NP_001032583
- UniProt
- P63167
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