Epidermal Growth Factor Receptor (EGFR) (Middle Region) Peptide
EGFR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EGFR products
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VTDHGSCVRA CGADSYEMEE DGVRKCKKCE GPCRKVCNGI GIGEFKDSLS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EGFR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Synonyms
- C-erb Peptide, CG10079 Peptide, D-EGFR Peptide, D-Egf Peptide, DEGFR Peptide, DER Peptide, DER flb Peptide, DER/EGFR Peptide, DER/faint little ball Peptide, DER/top Peptide, DER/torpedo Peptide, DER1 Peptide, DEgfr Peptide, Degfr Peptide, Der Peptide, DmHD-33 Peptide, Dmel\\CG10079 Peptide, EFG-R Peptide, EGF-R Peptide, EGFR Peptide, EGFr Peptide, EGfr Peptide, EK2-6 Peptide, Egf Peptide, Egf-r Peptide, EgfR Peptide, El Peptide, Elp Peptide, Elp-1 Peptide, Elp-B1 Peptide, Elp-B1RB1 Peptide, HD-33 Peptide, TOP Peptide, Torpedo/DER Peptide, Torpedo/Egfr Peptide, c-erbB Peptide, d-egf-r Peptide, dEGFR Peptide, dEGFR1 Peptide, dEgfr Peptide, der Peptide, egfr Peptide, flb Peptide, l(2)05351 Peptide, l(2)09261 Peptide, l(2)57DEFa Peptide, l(2)57EFa Peptide, l(2)57Ea Peptide, mor1 Peptide, top Peptide, top/DER Peptide, top/flb Peptide, torpedo/Egfr Peptide, torpedo/egfr Peptide, EGFR12 Peptide, EGFR15 Peptide, egfr1 Peptide, Erbb2 Peptide, ERBB Peptide, ERBB1 Peptide, HER1 Peptide, PIG61 Peptide, mENA Peptide, ErbB-1 Peptide, Errp Peptide, 9030024J15Rik Peptide, AI552599 Peptide, Erbb Peptide, Errb1 Peptide, Wa5 Peptide, wa-2 Peptide, wa2 Peptide, epidermal growth factor receptor Peptide, Epidermal growth factor receptor Peptide, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) Peptide, EGFR Peptide, Egfr Peptide, egfra Peptide, egfr1 Peptide, LOC5564544 Peptide
- Background
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The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Alias Symbols: ERBB, ERBB1, HER1, PIG61, mENA
Protein Interaction Partner: CALM1,CD44,CDH1,EGF,EGFR,ERBB2,GRB2,HSP90AA1,MUC1,PAK1,PIK3R1,PIK3R2,PLCG1,PLD2,RASA1,SHC1,SHC1,SHC1,STAT3,VAV2,ACTA1,ADRBK1,AGTR1,ALCAM,AMH,ANXA1,AR,AREG,ARF4,ATP1A1,ATP1B1,ATP5C1,BTC,CALM1,CALM3,CALM3,CAMK2A,CAMK2G,CAMLG,CASP1,CAV1,CAV2,CAV3,CBL,CBLB,CB
Protein Size: 628 - Molecular Weight
- 69 kDa
- Gene ID
- 1956
- NCBI Accession
- NM_201282, NP_958439
- UniProt
- P00533
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