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G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) (C-Term) Peptide

GPBAR1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN977577
  • Target See all GPBAR1 products
    GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    AAAVPVAMGL GDQRYTAPWR AAAQRCLQGL WGRASRDSPG PSIAYHPSSQ
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-GPBAR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
    Synonyms
    BG37 Peptide, GPCR19 Peptide, GPR131 Peptide, M-BAR Peptide, TGR5 Peptide, Tgr5 Peptide, MGC84403 Peptide, GPBAR1 Peptide, Gpbar1 Peptide, GPCR Peptide, G protein-coupled bile acid receptor 1 Peptide, G protein-coupled bile acid receptor 1 S homeolog Peptide, GPBAR1 Peptide, Gpbar1 Peptide, gpbar1.S Peptide
    Background
    This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.

    Alias Symbols: BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5

    Protein Size: 330
    Molecular Weight
    35 kDa
    Gene ID
    151306
    NCBI Accession
    NM_170699, NP_733800
    UniProt
    Q8TDU6
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