Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (Middle Region) Peptide
GRIN2B
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all GRIN2B products
- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GRIN2B antibody (Catalog #: ARP35015_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
- Synonyms
- NMDAR2B Peptide, GluN2B Peptide, MRD6 Peptide, NR2B Peptide, hNR3 Peptide, nmdar2b Peptide, nr2b Peptide, AW490526 Peptide, Nmdar2b Peptide, glutamate ionotropic receptor NMDA type subunit 2B Peptide, glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog Peptide, glutamate receptor, ionotropic, NMDA2B (epsilon 2) Peptide, GRIN2B Peptide, Grin2b Peptide, grin2b.L Peptide
- Background
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GRIN2B is the NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. Sequence Note: This RefSeq was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-544 U90278.1 31-574 545-545 U88963.1 545-545 546-3677 U90278.1 576-3707 3678-5941 AC007535.3 145452-147715
Alias Symbols: MGC142178, MGC142180, NMDAR2B, NR2B, hNR3, MRD6, GluN2B
Protein Interaction Partner: MAGI3,ACTN2,AP1M1,AP2M1,AP4M1,ARHGAP32,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAMK2N1,CAPN1,DLG1,DLG2,DLG3,DLG4,EPHB2,EXOC4,FYN,GNB2L1,GRIN1,GRIN2B,GRIN3A,IL16,INADL,LIN7A,LIN7B,MAGI3,PARK2,PIK3CA,PLCG1,PRKCA,PRKCB,PRKCG,PTPN11,SRC,SYNGAP1,TANC1,ACTN2,ARHGAP32,CAMK2A,DLG1,DLG2,DLG3,DLG4,Dlgap2,ERBB2IP,EXOC3,EXOC4,EXOC7,FYN,GNB2L1,GRIN1,IL16,LIN7A,LIN7B,MIB2,PARK2,UBC
Protein Size: 1484 - Molecular Weight
- 163 kDa
- Gene ID
- 2904
- NCBI Accession
- NM_000834, NP_000825
- UniProt
- Q13224
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