Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA) (C-Term) Peptide
GZMA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GZMA products
- GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LRGGRDSCNG DSGSPLLCEG VFRGVTSFGL ENKCGDPRGP GVYILLSKKH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GZMA Antibody(ARP54794_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
- Synonyms
- gzmA Peptide, GZMA Peptide, AW494114 Peptide, Ctla-3 Peptide, Ctla3 Peptide, Hf Peptide, SE1 Peptide, TSP-1 Peptide, TSP1 Peptide, CTLA3 Peptide, HFSP Peptide, granzyme A Peptide, Granzyme A Peptide, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) Peptide, gzmA Peptide, GZMA Peptide, graa Peptide, Gzma Peptide
- Background
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Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
Alias Symbols: CTLA3, HFSP
Protein Interaction Partner: APEX1,GZMA,HMGB2,LMNB1,NCL,SET,HMGB2,SET
Protein Size: 262 - Molecular Weight
- 26 kDa
- Gene ID
- 3001
- NCBI Accession
- NM_006144, NP_006135
- UniProt
- P12544
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