Heart and Neural Crest Derivatives Expressed 1 (HAND1) (N-Term) Peptide
HAND1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HAND1 products
- HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CHQERPYFQS WLLSPADAAP DFPAGGPPPA AAAAATAYGP DARPGQSPGR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HAND1 Antibody(ARP33748_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))
- Synonyms
- CATG Peptide, CG Peptide, Hxt Peptide, Thing1 Peptide, bHLHa27 Peptide, eHand Peptide, eHAND Peptide, hand-1 Peptide, hand1-A Peptide, HXT Peptide, HAND1 Peptide, hxt Peptide, thing1 Peptide, EHAND Peptide, Hand1 Peptide, Ehand1 Peptide, Th1 Peptide, cathepsin G Peptide, heart and neural crest derivatives expressed 1 Peptide, heart and neural crest derivatives expressed 1 L homeolog Peptide, CTSG Peptide, HAND1 Peptide, Hand1 Peptide, hand1.L Peptide, hand1 Peptide
- Background
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The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Alias Symbols: Hxt, eHand, Thing1, bHLHa27, HAND1
Protein Interaction Partner: ACHE,FHL2,HAND1,HAND2,HEY2,HEYL,MYOD1,PPP2R5D,PRKACA,PRKCA,TCF12,TCF3,HEY2,HEYL,PPP2R5D,PRKACA,PRKCA
Protein Size: 215 - Molecular Weight
- 23 kDa
- Gene ID
- 9421
- NCBI Accession
- NM_004821, NP_004812
- UniProt
- O96004
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