Homer Homolog 3 (Drosophila) (HOMER3) (N-Term) Peptide
HOMER3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HOMER3 products
- HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DSRANTVYGL GFASEQHLTQ FAEKFQEVKE AARLAREKSQ DGGELTSPAL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HOMER3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))
- Synonyms
- zgc:55557 Peptide, HOMER-3 Peptide, VESL3 Peptide, AW146114 Peptide, Vesl-3 Peptide, homer scaffolding protein 3b Peptide, homer scaffolding protein 3 Peptide, homer3b Peptide, HOMER3 Peptide, Homer3 Peptide
- Background
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This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
Alias Symbols: HOMER-3, VESL3
Protein Interaction Partner: GRM5,CEBPB,DYNLL2,FAT1,GRM5,HOMER1,ITPR1,PAX6,RYR1,DYNLL2,FRYL,RYR1,TRPC1,TRPC4,TRPC5
Protein Size: 358 - Molecular Weight
- 39 kDa
- Gene ID
- 9454
- NCBI Accession
- NM_001145721, NP_001139193
- UniProt
- Q9NSC5
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