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Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA) (N-Term) Peptide

IL28RA Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978504
  • Target See all IL28RA products
    IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-IL28RA antibody (Catalog #: ARP48069_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
    Synonyms
    IFNLR1 Peptide, IL28RA Peptide, crf2/12 Peptide, ifnlr Peptide, il-28r1 Peptide, il28ra Peptide, licr2 Peptide, ifnlr1 Peptide, CRF2-12 Peptide, Il28ra Peptide, CRF2/12 Peptide, IFNLR Peptide, IL-28R1 Peptide, LICR2 Peptide, RGD1562689 Peptide, interferon lambda receptor 1 Peptide, interferon, lambda receptor 1 Peptide, interferon, lambda receptor 1 L homeolog Peptide, IFNLR1 Peptide, ifnlr1 Peptide, ifnlr1.L Peptide, Ifnlr1 Peptide
    Background
    IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Alias Symbols: CRF2/12, IFNLR, IFNLR1, LICR2, il-28r1, IL-28R1, IL28RA

    Protein Interaction Partner: IL28A,IL28RA,IL29,NAA38,NAA38

    Protein Size: 491
    Molecular Weight
    54 kDa
    Gene ID
    163702
    NCBI Accession
    NM_173064, NP_775087
    UniProt
    Q5VTX8
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