Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4) (Middle Region) Peptide
KCNJ4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KCNJ4 products
- KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KCNJ4 antibody (Catalog #: ARP35167_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))
- Synonyms
- KCNJ4 Peptide, CKIR2.3 Peptide, HIR Peptide, HIRK2 Peptide, HRK1 Peptide, IRK-3 Peptide, IRK3 Peptide, Kir2.3 Peptide, Kcnf2 Peptide, MB-IRK3 Peptide, Hirk2 Peptide, potassium voltage-gated channel subfamily J member 4 Peptide, potassium inwardly-rectifying channel, subfamily J, member 4 Peptide, KCNJ4 Peptide, Kcnj4 Peptide
- Background
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KCNJ4 is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have??een found for this gene. Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neuronsSeveral different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: HIR, HIRK2, HRK1, IRK3, Kir2.3, MGC142066, MGC142068, IRK-3
Protein Interaction Partner: CASK,DLG1,DLG2,DLG4,GNGT2,IL16,KCNJ2,LIN7B,PRKCD,CASK,DLG1,DLG2,DLG4,DMD,GNGT2,IL16,LIN7A,LIN7B,LIN7C,SNTA1
Protein Size: 445 - Molecular Weight
- 49 kDa
- Gene ID
- 3761
- NCBI Accession
- NM_004981, NP_004972
- UniProt
- P48050
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