Latrophilin 1 (LPHN1) (C-Term) Peptide
LPHN1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Latrophilin 1 (LPHN1) products
- Latrophilin 1 (LPHN1)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YSLRSGDFPP GDGGPEPPRG RNLADAAAFE KMIISELVHN NLRGSSSAAK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LPHN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Latrophilin 1 (LPHN1)
- Synonyms
- LPHN1 Peptide, CIRL1 Peptide, CL1 Peptide, LEC2 Peptide, 2900070I05Rik Peptide, AI182398 Peptide, CLIBA Peptide, Lec2 Peptide, mKIAA0821 Peptide, CL1BA Peptide, adhesion G protein-coupled receptor L1 Peptide, ADGRL1 Peptide, Adgrl1 Peptide
- Background
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This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane.
Alias Symbols: CIRL1, CL1, LEC2
Protein Size: 839 - Molecular Weight
- 95 kDa
- Gene ID
- 22859
- NCBI Accession
- NM_001008701
- UniProt
- O94910
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