Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8) (N-Term) Peptide
MAP3K8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MAP3K8 products
- MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAP3K8 antibody (Catalog #: ARP30650_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))
- Synonyms
- MAP3K8 Peptide, COT Peptide, EST Peptide, ESTF Peptide, MEKK8 Peptide, TPL2 Peptide, Tpl-2 Peptide, c-COT Peptide, Cot Peptide, Cot/Tpl2 Peptide, Est Peptide, Estf Peptide, Tpl2 Peptide, D17TPL2 Peptide, mitogen-activated protein kinase kinase kinase 8 Peptide, MAP3K8 Peptide, map3k8 Peptide, Map3k8 Peptide
- Background
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MAP3K8 is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways. This kinase was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This kinase was
Alias Symbols: COT, EST, ESTF, FLJ10486, TPL2, Tpl-2, c-COT, MEKK8
Protein Interaction Partner: AKT1,BMPR2,CD40,CHUK,MAP2K4,MAP3K14,NFKB1,NFKB2,REL,RELA,RIPK1,TNIP2,TRAF2,TRAF6,AKT1,CHUK,KSR2,MAP2K1,MAP2K4,MAP3K14,NFKB1,NFKB2,REL,RELA,TNIP2,TRAF2
Protein Size: 467 - Molecular Weight
- 53 kDa
- Gene ID
- 1326
- NCBI Accession
- NM_005204, NP_005195
- UniProt
- P41279
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