Mitogen-Activated Protein Kinase 7 (MAPK7) (Middle Region) Peptide
MAPK7
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all MAPK7 products
- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- FDMGVADGPQ DGQADSASLS ASLLADWLEG HGMNPADIES LQREIQMDSP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAPK7 Antibody(ARP57731_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
- Synonyms
- BMK1 Peptide, ERK4 Peptide, ERK5 Peptide, PRKM7 Peptide, Erk5-T Peptide, ATMPK7 Peptide, F8D23.5 Peptide, F8D23_5 Peptide, MAP kinase 7 Peptide, Bmk1 Peptide, Erk5 Peptide, Prkm7 Peptide, ERK-5 Peptide, bmk1 Peptide, erk4 Peptide, mapk7 Peptide, prkm7 Peptide, mitogen-activated protein kinase 7 Peptide, MAP kinase 7 Peptide, mitogen-activated protein kinase 7 L homeolog Peptide, MAPK7 Peptide, Mapk7 Peptide, MPK7 Peptide, mapk7.L Peptide
- Background
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
Alias Symbols: BMK1, ERK4, ERK5, PRKM7
Protein Interaction Partner: MAP2K5,ELK4,ETS1,GJA1,MAP2K5,MEF2A,MEF2C,MEF2D,MYC,PTPRR,RAF1,RXRA,SGK1,YWHAB,GJA1,GOLGB1,MAP2K5,MAPK7,MEF2A,MEF2C,MEF2C,MEF2D,PTPRR,RAF1,SGK1,SLT2,YWHAB,YWHAE
Protein Size: 816 - Molecular Weight
- 88 kDa
- Gene ID
- 5598
- NCBI Accession
- NM_139034, NP_620603
- UniProt
- Q13164
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