Minichromosome Maintenance Complex Component 6 (MCM6) Peptide
MCM6
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all MCM6 products
- MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MCM6 antibody (Catalog #: ARP36650_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
- Synonyms
- CG4039 Peptide, DmMCM6 Peptide, DmeMCM6 Peptide, Dmel\\CG4039 Peptide, MCM6 Peptide, McM6 Peptide, fs(1)K1214 Peptide, mcm6 Peptide, MCG40308 Peptide, Mis5 Peptide, P105MCM Peptide, Mcmd6 Peptide, mis5 Peptide, mmcm6 Peptide, ASP-l1 Peptide, D1Wsu22e Peptide, Minichromosome maintenance 6 Peptide, DNA replication licensing factor MCM6 Peptide, minichromosome maintenance complex component 6 Peptide, minichromosome maintenance complex component 6 L homeolog Peptide, DNA replication licensing factor mcm-6 Peptide, Mcm6 Peptide, TP02_0113 Peptide, PVX_114735 Peptide, CMU_027970 Peptide, MCM6 Peptide, mcm6.L Peptide, mcm-6 Peptide
- Background
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The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Alias Symbols: MCG40308, Mis5, P105MCM
Protein Interaction Partner: MCM2,MCM2,MCM4,MCM4,MCM6,ALS2CR11,CCNA1,CDT1,CRLS1,GMNN,IL1F5,ING5,MCM10,MCM2,MCM3,MCM4,MCM6,MCM7,MCM8,MLLT3,ORC2L,ORC6L,PSMA1,SCNM1,SMC1A,AIRE,ALS2CR11,CDC45,CDT1,IL1F5,ING5,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCM8,MLLT3,ORC1L,ORC2L,ORC4L,PMS1,PSMA1,RPA1,SCNM1,TAF10,TNFAIP3,USP49,USP7
Protein Size: 821 - Molecular Weight
- 90 kDa
- Gene ID
- 4175
- NCBI Accession
- NM_005915, NP_005906
- UniProt
- Q14566
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