Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (C-Term) Peptide
NFAT1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all NFAT1 products
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- PTVIQQQNAT SQRAAKNGPP VSDQKEVLPA GVTIKQEQNL DQTYLDDVNE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NFATC2 Antibody(ARP38988_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
- Synonyms
- NFATC2 Peptide, AI607462 Peptide, NF-ATc2 Peptide, NFAT1 Peptide, NFAT1-D Peptide, Nfatp Peptide, NFATP Peptide, nuclear factor of activated T-cells 2 Peptide, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 Peptide, NFATC2 Peptide, nfatc2 Peptide, Nfatc2 Peptide
- Background
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This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: NFAT1, NFATP
Protein Size: 925 - Molecular Weight
- 100 kDa
- Gene ID
- 4773
- NCBI Accession
- NM_173091, NP_775114
- UniProt
- Q13469
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