Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (C-Term) Peptide
NTRK2
Reactivity: Human
Host: Synthetic
BP, IHC, WB, IF
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- Target See all TRKB (NTRK2) products
- TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- DFSWFGFGKV KSRQGVGPAS VISNDDDSAS PLHHISNGSN TPSSSEGGPD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NTRK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
- Synonyms
- trkb Peptide, trkb-b Peptide, xtrkb Peptide, si:ch211-220b11.1 Peptide, trkB2 Peptide, NTRK2 Peptide, ntrk2 Peptide, gp145-trkb Peptide, TRKB Peptide, GP145-TrkB Peptide, trk-B Peptide, AI848316 Peptide, C030027L06Rik Peptide, Tkrb Peptide, trkB Peptide, RATTRKB1 Peptide, TRKB1 Peptide, Trk-B Peptide, TrkB Peptide, neurotrophic receptor tyrosine kinase 2 Peptide, neurotrophic receptor tyrosine kinase 2 L homeolog Peptide, neurotrophic tyrosine kinase, receptor, type 2b Peptide, neurotrophic receptor tyrosine kinase 2 S homeolog Peptide, neurotrophic tyrosine kinase, receptor, type 2 Peptide, NTRK2 Peptide, ntrk2.L Peptide, ntrk2b Peptide, ntrk2.S Peptide, ntrk2 Peptide, Ntrk2 Peptide
- Background
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This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders.
Alias Symbols: GP145-TrkB, TRKB, trk-B
Protein Interaction Partner: NTF4,NTF4,NTF4,NTF4,BDNF,DOK5,DYNLL1,FRS3,FYN,GIPC1,KIDINS220,NCK1,NCK2,NGFR,NTF3,NTF4,NTRK2,PLCG1,PTPN1,PTPN11,RASGRF1,SH2B1,SH2B2,SHC1,SHC2,SHC3,SQSTM1,UBB,BDNF,DYNLL1,FRS2,FYN,GIPC1,NCK2,NTF3,NTF4,PIK3R1,PLCG1,PTPN1,SH2B1,SHC1,SHC3,SQSTM1,TRAF6,UBC
Protein Size: 553 - Molecular Weight
- 57 kDa
- Gene ID
- 4915
- NCBI Accession
- NM_001018065, NP_001018075
- UniProt
- Q8WXJ5
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