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Oxytocin, Prepropeptide (OXT) (N-Term) Peptide

OXT Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981259
  • Target See all OXT products
    OXT (Oxytocin, Prepropeptide (OXT))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    LGLLALTSAC YIQNCPLGGK RAAPDLDVRK CLPCGPGGKG RCFGPNICCA
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-OXT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    OXT (Oxytocin, Prepropeptide (OXT))
    Synonyms
    OT Peptide, OT-NPI Peptide, OXT-NPI Peptide, Oxy Peptide, OTNPI Peptide, NEURL1 Peptide, RNF67 Peptide, bA416N2.1 Peptide, neu Peptide, neu-1 Peptide, Ocytocin Peptide, Oxytocin Peptide, oxytocin/neurophysin I prepropeptide Peptide, oxytocin Peptide, oxytocin/neurophysin 1 prepropeptide Peptide, neuralized E3 ubiquitin protein ligase 1 Peptide, vasopressin-neurophysin 2 Peptide, OXT Peptide, Oxt Peptide, NEURL1 Peptide, LOC100066842 Peptide
    Background
    There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.

    Alias Symbols: MGC126890, MGC126892, OT, OT-NPI

    Protein Interaction Partner: ESR2,OXTR,PREP,TXNDC17,MLL,TXNDC17

    Protein Size: 125
    Molecular Weight
    9 kDa
    Gene ID
    5020
    NCBI Accession
    NM_000915, NP_000906
    UniProt
    P01178
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