phosphodiesterase 8A (PDE8A) (C-Term) Peptide
PDE8A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PDE8A products
- PDE8A (phosphodiesterase 8A (PDE8A))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SSNPYHNSTH SADVLHATAY FLSKERIKET LDPIDEVAAL IAATIHDVDH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PDE8A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDE8A (phosphodiesterase 8A (PDE8A))
- Synonyms
- PDE8A Peptide, Pde8a Peptide, HsT19550 Peptide, AI551852 Peptide, Pde8 Peptide, RNPDE8A Peptide, phosphodiesterase 8A Peptide, PDE8A Peptide, Pde8a Peptide, pde8a Peptide
- Background
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Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., MIM 2000).
Alias Symbols: FLJ16150, HsT19550
Protein Size: 829 - Molecular Weight
- 91 kDa
- Gene ID
- 5151
- NCBI Accession
- NM_002605, NP_002596
- UniProt
- O60658
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