phosphodiesterase 8B (PDE8B) (Middle Region) Peptide
PDE8B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PDE8B products
- PDE8B (phosphodiesterase 8B (PDE8B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TELYSPQLGT KDEDPHTSDL VGGLMTDGLR RLSGNEYVFT KNVHQSHSHL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PDE8B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDE8B (phosphodiesterase 8B (PDE8B))
- Synonyms
- PDE8B Peptide, ADSD Peptide, PPNAD3 Peptide, B230331L10Rik Peptide, C030047E14Rik Peptide, RNPDE8B Peptide, phosphodiesterase 8B Peptide, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B Peptide, PDE8B Peptide, LOC100468338 Peptide, pde8b Peptide, Pde8b Peptide
- Background
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The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADSD, FLJ11212, PPNAD3
Protein Size: 788 - Molecular Weight
- 87 kDa
- Gene ID
- 8622
- NCBI Accession
- NM_001029851, NP_001025022
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