Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) Peptide
PDK4
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all PDK4 products
- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PDK4 antibody (Catalog #: ARP32787_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
- Synonyms
- AV005916 Peptide, pyruvate dehydrogenase kinase 4 Peptide, pyruvate dehydrogenase kinase, isoenzyme 4 Peptide, pdk4 Peptide, PDK4 Peptide, Pdk4 Peptide
- Background
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PDK4 is a member of the PDK/BCKDK protein kinase family and is a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
Alias Symbols: FLJ40832
Protein Interaction Partner: DLAT,PDHA1,PDK4,TRIM63
Protein Size: 411 - Molecular Weight
- 46 kDa
- Gene ID
- 5166
- NCBI Accession
- NM_002612, NP_002603
- UniProt
- Q16654
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