phosphofructokinase, Muscle (PFKM) (C-Term) Peptide
PFKM
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PFKM products
- PFKM (phosphofructokinase, Muscle (PFKM))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RALVFQPVAE LKDQTDFEHR IPKEQWWLKL RPILKILAKY EIDLDTSDHA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PFKM Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PFKM (phosphofructokinase, Muscle (PFKM))
- Synonyms
- GSD7 Peptide, PFK-1 Peptide, PFK1 Peptide, PFKA Peptide, PFKX Peptide, AI131669 Peptide, PFK-A Peptide, PFK-M Peptide, Pfk-4 Peptide, Pfk4 Peptide, Pfka Peptide, Pfkx Peptide, Pfk-M Peptide, M-PFK Peptide, PFKM Peptide, pfkm Peptide, zgc:92344 Peptide, pfk Peptide, im:7137110 Peptide, wu:fc58g11 Peptide, phosphofructokinase, muscle Peptide, phosphofructokinase, platelet Peptide, phosphofructokinase, muscle a Peptide, phosphofructokinase, muscle S homeolog Peptide, phosphofructokinase, muscle b Peptide, PFKM Peptide, Pfkm Peptide, PFKP Peptide, pfkma Peptide, pfkm.S Peptide, pfkmb Peptide
- Background
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Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Alias Symbols: GSD7, MGC8699, PFK-1, PFK1, PFKA, PFKX
Protein Interaction Partner: ATP6V0A4,CAV3,DYNLL1,FHL2,NOS1,PFKL,ATP6V0A4,CAV3,FHL2,HGS,SUMO1,SUMO2
Protein Size: 780 - Molecular Weight
- 85 kDa
- Gene ID
- 5213
- NCBI Accession
- NM_000289, NP_000280
- UniProt
- P08237
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