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Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) (N-Term) Peptide

PI4K2B Reactivity: Mouse Host: Synthetic BP, WB
Catalog No. ABIN981721
  • Target See all PI4K2B products
    PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))
    Protein Region
    N-Term
    Origin
    Mouse
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    EDPEFADIVL KAEQAIEIGV FPERISQGSS GSYFVKDSKR NIIGVFKPKS
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-Pi4k2b Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))
    Synonyms
    GB16449 Peptide, pi4kiib Peptide, pik42b Peptide, PI4KIIB Peptide, PIK42B Peptide, 2610042N09Rik Peptide, 4933409G22Rik Peptide, zgc:158305 Peptide, uncharacterized LOC725812 Peptide, phosphatidylinositol 4-kinase type 2 beta L homeolog Peptide, phosphatidylinositol 4-kinase type 2 beta Peptide, LOC725812 Peptide, pi4k2b.L Peptide, PI4K2B Peptide, pi4k2b Peptide, Pi4k2b Peptide
    Background
    Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) Pi4k2b contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Pi4k2b contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.

    Alias Symbols: 2610042N09Rik, 4933409G22Rik

    Protein Size: 469
    Molecular Weight
    52 kDa
    Gene ID
    67073
    NCBI Accession
    NM_025951, NP_080227
    UniProt
    Q8CBQ5
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