Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) (N-Term) Peptide
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- Target See all PI4K2B products
- PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))
- Protein Region
- N-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EDPEFADIVL KAEQAIEIGV FPERISQGSS GSYFVKDSKR NIIGVFKPKS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Pi4k2b Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))
- Synonyms
- GB16449 Peptide, pi4kiib Peptide, pik42b Peptide, PI4KIIB Peptide, PIK42B Peptide, 2610042N09Rik Peptide, 4933409G22Rik Peptide, zgc:158305 Peptide, uncharacterized LOC725812 Peptide, phosphatidylinositol 4-kinase type 2 beta L homeolog Peptide, phosphatidylinositol 4-kinase type 2 beta Peptide, LOC725812 Peptide, pi4k2b.L Peptide, PI4K2B Peptide, pi4k2b Peptide, Pi4k2b Peptide
- Background
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Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) Pi4k2b contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Pi4k2b contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
Alias Symbols: 2610042N09Rik, 4933409G22Rik
Protein Size: 469 - Molecular Weight
- 52 kDa
- Gene ID
- 67073
- NCBI Accession
- NM_025951, NP_080227
- UniProt
- Q8CBQ5
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