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GPI-anchor transamidase (GPI8) Peptide

GPI8 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981743
  • Target See all PIGK (GPI8) products
    PIGK (GPI8) (GPI-anchor transamidase (GPI8))
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PIGK antibody (Catalog #: ARP40587_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PIGK (GPI8) (GPI-anchor transamidase (GPI8))
    Synonyms
    GPI8 Peptide, 3000001O05Rik Peptide, zgc:86702 Peptide, phosphatidylinositol glycan anchor biosynthesis class K S homeolog Peptide, phosphatidylinositol glycan anchor biosynthesis class K Peptide, phosphatidylinositol glycan anchor biosynthesis, class K Peptide, pigk.S Peptide, PIGK Peptide, Pigk Peptide, pigk Peptide
    Background
    PIGK is a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGK is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: GPI8, MGC22559

    Protein Interaction Partner: ALPP,GPAA1,PIGT,ALPP,CANX,GPAA1,PIGT,ULBP2

    Protein Size: 395
    Molecular Weight
    43 kDa
    Gene ID
    10026
    NCBI Accession
    NM_005482, NP_005473
    UniProt
    Q92643
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