Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ) (N-Term) Peptide
PIGZ
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PIGZ products
- PIGZ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PIGZ antibody (Catalog #: ARP41020_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PIGZ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))
- Synonyms
- F630022B06Rik Peptide, GPI-MT-IV Peptide, PIG-Z Peptide, SMP3 Peptide, phosphatidylinositol glycan anchor biosynthesis, class Z Peptide, phosphatidylinositol glycan anchor biosynthesis class Z Peptide, Pigz Peptide, PIGZ Peptide
- Background
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The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. PIGZ is a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.
Alias Symbols: FLJ12768, GPI-MT-IV, MGC52163, SMP3, PIG-Z
Protein Size: 579 - Molecular Weight
- 63 kDa
- Gene ID
- 80235
- NCBI Accession
- NM_025163, NP_079439
- UniProt
- Q86VD9
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