Pyruvate Kinase M2 (PKM2) (Middle Region) Peptide
PKM2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PKM2 products
- PKM2 (Pyruvate Kinase M2 (PKM2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- HLQLFEELRR LAPITSDPTE ATAVGAVEAS FKCCSGAIIV LTKSGRSAHQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PKM2 Antibody(ARP57789_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PKM2 (Pyruvate Kinase M2 (PKM2))
- Synonyms
- CTHBP Peptide, OIP3 Peptide, PK3 Peptide, PKM2 Peptide, TCB Peptide, THBP1 Peptide, AA414905 Peptide, AL024370 Peptide, AL024424 Peptide, Pk-2 Peptide, Pk-3 Peptide, Pk3 Peptide, Pkm2 Peptide, PKM12 Peptide, PKM Peptide, pyruvate kinase M1/2 Peptide, pyruvate kinase, muscle Peptide, PKM Peptide, Pkm Peptide
- Background
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This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Alias Symbols: CTHBP, MGC3932, OIP3, PK3, PKM, TCB, THBP1, PKM2
Protein Interaction Partner: RAF1,RAF1,ARAF,EXOSC5,HERC1,NDRG1,OLFM2,PKM2,RAF1,SHBG,SORBS2,ARAF,BANF1,EXOSC5,TRIM63
Protein Size: 531 - Molecular Weight
- 58 kDa
- Gene ID
- 5315
- NCBI Accession
- NM_002654, NP_002645
- UniProt
- P11980
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