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Plasminogen Activator, Tissue (PLAT) (Middle Region) Peptide

PLAT Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981837
  • Target See all PLAT products
    PLAT (Plasminogen Activator, Tissue (PLAT))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    TVILGRTYRV VPGEEEQKFE VEKYIVHKEF DDDTYDNDIA LLQLKSDSSR
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PLAT Antibody(ARP57691_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PLAT (Plasminogen Activator, Tissue (PLAT))
    Synonyms
    T-PA Peptide, TPA Peptide, AU020998 Peptide, AW212668 Peptide, D8Ertd2e Peptide, tPA Peptide, PATISS Peptide, tpa Peptide, Plat Peptide, plat Peptide, t-pa Peptide, plasminogen activator, tissue type Peptide, plasminogen activator, tissue Peptide, chromosome 20 open reading frame 181 Peptide, plasminogen activator, tissue L homeolog Peptide, PLAT Peptide, Plat Peptide, plat Peptide, C20orf181 Peptide, plat.L Peptide
    Background
    This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

    Alias Symbols: DKFZp686I03148, T-PA, TPA

    Protein Interaction Partner: ANXA2,CALR,CKAP4,CLEC3B,F10,FGA,GRIN1,HMGB1,KRT8,LAMA1,LAMA3,LRP1,LRP1B,MAPK1,MAPK3,PLAT,PLAU,PLG,SERPINA5,SERPINE1,SERPING1,SERPINI1,SPARC,ANXA2,CALR,CLEC3B,F10,F2,FGA,FN1,HMGB1,KRT8,LAMA1,LAMA5,LRP1,PLAU,SERPINA5,SERPINE1,SERPINI1

    Protein Size: 516
    Molecular Weight
    53 kDa
    Gene ID
    5327
    NCBI Accession
    NM_033011, NP_127509
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