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P450 (Cytochrome) Oxidoreductase (POR) Peptide

POR Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN981990
  • Target See all POR products
    POR (P450 (Cytochrome) Oxidoreductase (POR))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-POR antibody (Catalog #: ARP44362_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    POR (P450 (Cytochrome) Oxidoreductase (POR))
    Synonyms
    CPR Peptide, CYPOR Peptide, P450R Peptide, POR Peptide, CCR Peptide, CG11567 Peptide, DMR Peptide, DmCPR Peptide, Dmel\\CG11567 Peptide, NCPR Peptide, P450 Peptide, cpr Peptide, zgc:110032 Peptide, npr Peptide, xpor Peptide, 4933424M13Rik Peptide, PORCINO Peptide, T5J17.90 Peptide, T5J17_90 Peptide, TFC C Peptide, TUBULIN-FOLDING COFACTOR C Peptide, cytochrome p450 oxidoreductase Peptide, P450 (cytochrome) oxidoreductase Peptide, ADP-ribosylation factor interacting protein 2 Peptide, Cytochrome P450 reductase Peptide, P450 (cytochrome) oxidoreductase a Peptide, P450 (cytochrome) oxidoreductase L homeolog Peptide, NADPH--cytochrome P450 reductase Peptide, C-CAP/cofactor C-like domain-containing protein Peptide, POR Peptide, Arfip2 Peptide, Por Peptide, Cpr Peptide, pora Peptide, por.L Peptide, LOC100406157 Peptide, por Peptide, LOC100619047 Peptide
    Background
    POR is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this POR gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CPR, CYPOR, DKFZp686G04235, FLJ26468, P450R

    Protein Interaction Partner: CYB5A,CYP17A1,CYP1A2,CYP2C19,CYP2C9,CYP2E1,HMOX1,XRCC6,CYP1A2,CYP2C19,CYP2C9,CYP2E1

    Protein Size: 680
    Molecular Weight
    77 kDa
    Gene ID
    5447
    NCBI Accession
    NM_000941, NP_000932
    UniProt
    Q63HL4
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