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Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) (Middle Region) Peptide

PPP1R13B Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982098
  • Target See all PPP1R13B products
    PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PPP1R13B antibody (Catalog #: ARP47979_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
    Synonyms
    ASPP1 Peptide, p53BP2-like Peptide, p85 Peptide, AI449786 Peptide, AW545810 Peptide, Tp53bp2 Peptide, Trp53bp2 Peptide, protein phosphatase 1 regulatory subunit 13B Peptide, protein phosphatase 1, regulatory subunit 13B Peptide, protein phosphatase 1 regulatory subunit 13B L homeolog Peptide, protein phosphatase 1, regulatory subunit 13Bb Peptide, protein phosphatase 1, regulatory (inhibitor) subunit 13B Peptide, PPP1R13B Peptide, Ppp1r13b Peptide, ppp1r13b.L Peptide, ppp1r13bb Peptide, ppp1r13b Peptide
    Background
    PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

    Alias Symbols: ASPP1, KIAA0771, p53BP2-like, p85

    Protein Interaction Partner: E2F1,E2F1,E2F2,E2F3,E2F4,PPP1CA,TP63,TP73

    Protein Size: 1090
    Molecular Weight
    119 kDa
    Gene ID
    23368
    NCBI Accession
    NM_015316, NP_056131
    UniProt
    Q96KQ4
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