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Poliovirus Receptor (PVR) (N-Term) Peptide

PVR Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN982486
  • Target See all Poliovirus Receptor (PVR) products
    Poliovirus Receptor (PVR)
    Protein Region
    N-Term
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Sequence
    FHQTQGPSYS ESKRLEFVAA RLGAELRNAS LRMFGLRVED EGNYTCLFVT
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PVR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Poliovirus Receptor (PVR)
    Synonyms
    PVR Peptide, CD155 Peptide, HVED Peptide, NECL5 Peptide, Necl-5 Peptide, PVS Peptide, TAGE4 Peptide, 3830421F03Rik Peptide, D7Ertd458e Peptide, Taa1 Peptide, Tage4 Peptide, mE4 Peptide, necl-5 Peptide, poliovirus receptor Peptide, PVR Peptide, Pvr Peptide
    Background
    The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CD155, FLJ25946, HVED, NECL5, Necl-5, PVS, TAGE4

    Protein Interaction Partner: VTN,AP1M2,CD226,CD96,DYNLT3,PVR,PVRL1,PVRL3,VTN,AP1M2,CD226,DYNLT1,PVRL3,VTN

    Protein Size: 417
    Molecular Weight
    45 kDa
    Gene ID
    5817
    NCBI Accession
    NM_006505, NP_006496
    UniProt
    P15151
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