Poliovirus Receptor (PVR) (N-Term) Peptide
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- Target See all Poliovirus Receptor (PVR) products
- Poliovirus Receptor (PVR)
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Sequence
- FHQTQGPSYS ESKRLEFVAA RLGAELRNAS LRMFGLRVED EGNYTCLFVT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PVR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Poliovirus Receptor (PVR)
- Synonyms
- PVR Peptide, CD155 Peptide, HVED Peptide, NECL5 Peptide, Necl-5 Peptide, PVS Peptide, TAGE4 Peptide, 3830421F03Rik Peptide, D7Ertd458e Peptide, Taa1 Peptide, Tage4 Peptide, mE4 Peptide, necl-5 Peptide, poliovirus receptor Peptide, PVR Peptide, Pvr Peptide
- Background
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The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD155, FLJ25946, HVED, NECL5, Necl-5, PVS, TAGE4
Protein Interaction Partner: VTN,AP1M2,CD226,CD96,DYNLT3,PVR,PVRL1,PVRL3,VTN,AP1M2,CD226,DYNLT1,PVRL3,VTN
Protein Size: 417 - Molecular Weight
- 45 kDa
- Gene ID
- 5817
- NCBI Accession
- NM_006505, NP_006496
- UniProt
- P15151
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