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Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (Middle Region) Peptide

RPS6KA2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN983261
  • Target See all RPS6KA2 products
    RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RPS6KA2 antibody (Catalog #: ARP56170_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
    Synonyms
    HU-2 Peptide, MAPKAPK1C Peptide, RSK Peptide, RSK3 Peptide, S6K-alpha Peptide, S6K-alpha2 Peptide, p90-RSK3 Peptide, pp90RSK3 Peptide, 90kDa Peptide, D17Wsu134e Peptide, Rps6ka-rs1 Peptide, Rsk3 Peptide, p90rsk Peptide, pp90rsk Peptide, ribosomal protein S6 kinase A2 Peptide, ribosomal protein S6 kinase, polypeptide 2 Peptide, Rps6ka2 Peptide, RPS6KA2 Peptide
    Background
    RPS6KA2 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3

    Protein Interaction Partner: MAPK1,BAD,CREB1,L1CAM,MAGI1,MAP2K1,MAPK1,MAPK3,RPS6KA2,SHANK1,CREBBP,FOS,JUN,MAPK1,MAPK3,MAPK3,RPS6KA2

    Protein Size: 733
    Molecular Weight
    81 kDa
    Gene ID
    6196
    NCBI Accession
    NM_021135, NP_066958
    UniProt
    Q15349
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