Stanniocalcin 2 (STC2) (C-Term) Peptide
STC2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Stanniocalcin 2 (STC2) products
- Stanniocalcin 2 (STC2)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PSSRETGRGA KGERGSKSHP NAHARGRVGG LGAQGPSGSS EWEDEQSEYS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-STC2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Stanniocalcin 2 (STC2)
- Synonyms
- STC2 Peptide, im:6908722 Peptide, stc2 Peptide, wu:fd13c01 Peptide, zgc:136650 Peptide, MGC145691 Peptide, STC-2 Peptide, STCRP Peptide, AW125853 Peptide, Stc2l Peptide, mustc2 Peptide, stanniocalcin 2 Peptide, stanniocalcin 2a Peptide, STC2 Peptide, stc2a Peptide, stc2 Peptide, Stc2 Peptide
- Background
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This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Alias Symbols: STC-2, STCRP
Protein Interaction Partner: ADAM11,AIFM1,ARHGEF40,ARRB2,CARHSP1,EIF2B3,PEBP1,POLR2C,POLR3F,PPP1R8,PTN,ADAM11,AIFM1,ARHGEF40,ARRB2,CARHSP1,EIF2B3,PEBP1,POLR2C,POLR3F,PPP1R8,PTN
Protein Size: 302 - Molecular Weight
- 31 kDa
- Gene ID
- 8614
- NCBI Accession
- NM_003714, NP_003705
- UniProt
- O76061
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