Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E) (N-Term) Peptide
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- Target See all TFAP2E products
- TFAP2E (Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TFAP2E antibody (Catalog #: ARP31976_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TFAP2E (Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E))
- Synonyms
- zgc:65882 Peptide, zgc:77338 Peptide, RGD1563297 Peptide, Tcfap2e Peptide, AP2E Peptide, AI505200 Peptide, AP-2e Peptide, transcription factor AP-2 epsilon Peptide, transcription factor AP-2 epsilon L homeolog Peptide, transcription factor AP-2, epsilon Peptide, tfap2e Peptide, Tfap2e Peptide, TFAP2E Peptide, tfap2e.L Peptide
- Background
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TFAP2E is the sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 epsilon may play a role in the development of the CNS and in cartilage differentiation
Alias Symbols: AP2E, MGC49007
Protein Size: 442 - Molecular Weight
- 46 kDa
- Gene ID
- 339488
- NCBI Accession
- NM_178548, NP_848643
- UniProt
- Q6VUC0
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