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Transducin-Like Enhancer Protein 2 (TLE2) Peptide

TLE2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985126
  • Target See all TLE2 products
    TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TLE2 antibody (Catalog #: ARP32347_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
    Synonyms
    TLE2 Peptide, ESG Peptide, ESG2 Peptide, GRG2 Peptide, Grg2 Peptide, mKIAA4188 Peptide, transducin like enhancer of split 2 Peptide, transducin-like enhancer of split 2 Peptide, TLE2 Peptide, Tle2 Peptide
    Background
    TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.

    Alias Symbols: ESG, ESG2, FLJ41188, GRG2

    Protein Interaction Partner: H3F3B,HMGB1,PRDM1,RUNX1,TLE1,UTY,HES1,PRDM1,TLE1,TLE2,UTY

    Protein Size: 743
    Molecular Weight
    80 kDa
    Gene ID
    7089
    NCBI Accession
    NM_003260, NP_003251
    UniProt
    Q04725
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