Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (N-Term) Peptide
TNFRSF1B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TNFRSF1B products
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SDQVETQACT REQNRICTCR PGWYCALSKQ EGCRLCAPLR KCRPGFGVAR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNFRSF1B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
- Synonyms
- CD120b Peptide, TBPII Peptide, TNF-R-II Peptide, TNF-R75 Peptide, TNFBR Peptide, TNFR1B Peptide, TNFR2 Peptide, TNFR80 Peptide, p75 Peptide, p75TNFR Peptide, TNF-RII/TNFRSF1B Peptide, TNFR-II Peptide, TNFRSF1B Peptide, TNF-R2 Peptide, TNF-alphaR2 Peptide, TNFRII Peptide, TNFalpha-R2 Peptide, Tnfr-1 Peptide, Tnfr2 Peptide, rank Peptide, zgc:163064 Peptide, TNF receptor superfamily member 1B Peptide, tumor necrosis factor receptor superfamily, member 1b Peptide, tumor necrosis factor receptor superfamily, member 1B Peptide, TNFRSF1B Peptide, Tnfrsf1b Peptide, tnfrsf1b Peptide
- Background
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Alias Symbols: CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
Protein Interaction Partner: TNF,TRAF2,BMX,CAV1,CSNK1A1,FANCD2,HIVEP3,KRT18,LTA,STAT1,TDP2,TNF,TRAF1,TRAF2,TRAF3,TRAIP,ASB3,CAV1,CSNK1A1,FANCD2,KRT18,SMURF2,TDP2,TNF,TNFRSF1B,TRAF1,TRAF2,TRAIP,TRIM37,UBC
Protein Size: 461 - Molecular Weight
- 46 kDa
- Gene ID
- 7133
- NCBI Accession
- NM_001066, NP_001057
- UniProt
- P20333
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