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UDP Glucuronosyltransferase 1 Family, Polypeptide A7 (UGT1A7) Peptide

UGT1A7 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN985906
  • Target See all UGT1A7 products
    UGT1A7 (UDP Glucuronosyltransferase 1 Family, Polypeptide A7 (UGT1A7))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-UGT1A7 antibody (Catalog #: ARP49438_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    UGT1A7 (UDP Glucuronosyltransferase 1 Family, Polypeptide A7 (UGT1A7))
    Synonyms
    UDPGT Peptide, UDPGT 1-7 Peptide, UGT-1G Peptide, UGT1-07 Peptide, UGT1.7 Peptide, UGT1G Peptide, UGT1A10 Peptide, UGT1A6 Peptide, UGT1A7 Peptide, UGT1A8 Peptide, UGT1A9 Peptide, UDP glucuronosyltransferase family 1 member A7 Peptide, UDP glucuronosyltransferase family 1 member A1 Peptide, UDP glucuronosyltransferase 1 family, polypeptide A7 Peptide, UGT1A7 Peptide, UGT1A1 Peptide, ugt1a7 Peptide
    Background
    UGT1A7 is an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: UDPGT, UGT1G, UGT-1G, UGT1.7, UGT1-07, UDPGT 1-7

    Protein Size: 530
    Molecular Weight
    57 kDa
    Gene ID
    54577
    NCBI Accession
    NM_019077, NP_061950
    UniProt
    Q5DSZ7
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