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Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) Peptide

VPS4A Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN986092
  • Target See all VPS4A products
    VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-VPS4A antibody (Catalog #: ARP54915_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
    Synonyms
    vsp4 Peptide, SKD1 Peptide, SKD1A Peptide, SKD2 Peptide, VPS4 Peptide, VPS4-1 Peptide, zgc:153907 Peptide, 4930589C15Rik Peptide, AI325971 Peptide, AW553189 Peptide, vacuolar protein sorting 4 homolog A Peptide, vacuolar sorting protein 4 Peptide, vacuolar protein sorting 4 homolog A L homeolog Peptide, vacuolar protein sorting 4a homolog A (S. cerevisiae) Peptide, vacuolar protein sorting 4A Peptide, VPS4A Peptide, TP03_0351 Peptide, vps4a Peptide, vps4a.L Peptide, Vps4a Peptide
    Background
    VPS4A is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast.The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: FLJ22197, SKD1, SKD2, VPS4, VPS4-1, SKD1A

    Protein Interaction Partner: CHMP4A,CHMP1A,CHMP1B,CHMP2A,CHMP4A,CHMP4B,CHMP4C,RND2,VPS4A,VPS4B,C19orf62,CHMP1A

    Protein Size: 437
    Molecular Weight
    49 kDa
    Gene ID
    27183
    NCBI Accession
    NM_013245, NP_037377
    UniProt
    Q9UN37
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