Wingless-Type MMTV Integration Site Family Member 2 (WNT2) (Middle Region) Peptide
WNT2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all WNT2 products
- WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-WNT2 antibody (Catalog #: ARP32124_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))
- Synonyms
- CG1916 Peptide, D-wnt-2 Peptide, DWnt-2 Peptide, DWnt2 Peptide, Dm DWnt2 Peptide, Dm-2 Peptide, Dmel\\CG1916 Peptide, Dwnt-2 Peptide, Wnt Peptide, Wnt-2 Peptide, dWnt2 Peptide, wnt2 Peptide, WNT2 Peptide, irp Peptide, Xwnt2 Peptide, wnt-2 Peptide, Xwnt-2 Peptide, int1l1 Peptide, 2610510E18Rik Peptide, Int1l1 Peptide, Irp Peptide, Mirp Peptide, Wnt2a Peptide, INT1L1 Peptide, IRP Peptide, ZfWnt2 Peptide, Wnt oncogene analog 2 Peptide, Wnt family member 2 Peptide, wingless-type MMTV integration site family member 2 Peptide, wingless-type MMTV integration site family, member 2 Peptide, Wnt2 Peptide, wnt2 Peptide, WNT2 Peptide
- Background
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WNT2 is the ligand for members of the frizzled family of seven transmembrane receptors. WNT2 is a probable developmental protein. WNT2 may be a signaling molecule which affects the development of discrete regions of tissues. WNT2 is likely to signal over only few cell diameters.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is expressed in the thalamus. It encodes a protein which shows 96 % amino acid identity to the mouse Wnt2 protein. Based on the map location of this gene in the 7q31 region, and the phenotype of the diminished social interaction in the knockout mouse, this gene is suggested as a strong candidate gene for autism, a prototypical pervasive development disorder. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: INT1L1, IRP
Protein Interaction Partner: FZD1,FZD9,SFRP1,WNT3A,SFRP1
Protein Size: 360 - Molecular Weight
- 38 kDa
- Gene ID
- 7472
- NCBI Accession
- NM_003391, NP_003382
- UniProt
- P09544
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