anti-Dog (Canine) AKT2 antibody for Immunohistochemistry

Recommended AKT2 Antibody (supplied by: Log in to see )

Antigen
V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Antibodies
  • AKT2
  • pkbb
  • pkbbeta
  • pkbss
  • prkbb
  • rac-beta
  • v-akt2
  • 2410016A19Rik
  • AW554154
  • PKB
  • PKBbeta
  • HIHGHH
  • PKBB
  • PKBBETA
  • PRKBB
  • RAC-BETA
  • cb945
  • akt2-a
  • AKT serine/threonine kinase 2
  • v-akt murine thymoma viral oncogene homolog 2
  • thymoma viral proto-oncogene 2
  • v-akt murine thymoma viral oncogene homolog 2 L homeolog
  • AKT2
  • akt2
  • Akt2
  • akt2.L
Epitope
Middle Region
62
56
25
23
23
20
12
12
9
8
8
6
5
5
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Zebrafish (Danio rerio)
480
197
158
54
51
46
44
43
41
40
40
40
23
18
3
2
2
1
1
1
Host
Rabbit
354
95
18
14
3
2
Clonality
Polyclonal
Conjugate
This AKT2 antibody is un-conjugated
24
22
19
19
18
16
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
422
272
198
95
62
50
37
34
31
20
13
11
8
5
4
4
3
2
1
Options
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Pubmed
1 reference available

Available images

Western Blotting (WB) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) antibody (ABIN2779323)
Western Blotting (WB) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) antibody (ABIN2779323)
Immunohistochemistry (IHC) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) antibody (ABIN2779323)
Immunohistochemistry (IHC) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) antibody (ABIN2779323)
Catalog No. ABIN2779323
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.96781 ABIN2792145 IHC WB Rabbit N-Term Log in to see Polyclonal 1
12.96781 ABIN2704466 IC IF IHC WB Rabbit C-Term Log in to see Polyclonal 0
9.96781 ABIN2957855 IHC WB Rabbit C-Term, pSer474 Log in to see Polyclonal 0
1 ABIN2615477 ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN2994519 IF/ICC IHC WB Rabbit Log in to see Polyclonal 0

General

Antigen V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Antibodies
Epitope Middle Region
(62), (56), (25), (23), (23), (20), (12), (12), (9), (8), (8), (6), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Zebrafish (Danio rerio)
(480), (197), (158), (54), (51), (46), (44), (43), (41), (40), (40), (40), (23), (18), (3), (2), (2), (1), (1), (1)
Host Rabbit
(354), (95), (18), (14), (3), (2)
Clonality
Polyclonal
Conjugate This AKT2 antibody is un-conjugated
(24), (22), (19), (19), (18), (16), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(422), (272), (198), (95), (62), (50), (37), (34), (31), (20), (13), (11), (8), (5), (4), (4), (3), (2), (1)
Pubmed 1 reference available
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Product Details anti-AKT2 Antibody

Target Details AKT2 Application Details Handling References for anti-AKT2 antibody (ABIN2779323) Images
Blocking Peptide Blocking peptide for this product available: ABIN973084
Sequence TSEVDTRYFD DEFTAQSITI TPPDRYDSLG LLELDQRTHF PQFSYSASIR
Predicted Reactivity Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against AKT2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human AKT2
Plasmids, Primers & others

Target Details AKT2

Product Details anti-AKT2 Antibody Application Details Handling References for anti-AKT2 antibody (ABIN2779323) Images back to top
Antigen
Alternative Name AKT2 (AKT2 Antibody Abstract)
Background AKT2 belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene encoding AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PKBBETA, PRKBB, RAC-BETA, PKBB, HIHGHH
Protein Interaction Partner: CLIP3, CHUK, PLEKHO1, PRKCZ, UBC, EGFR, POLR1B, SNX27, PNPLA3, STEAP4, ABCG8, POFUT1, TMED2, NAMPT, SORBS2, SPRR2A, CCL14, PRKDC, MAP3K5, HSP90AA1, APOB, APOA1, APPL1, APP, FSHR, VIM, SKI, GRK5, SH3RF1, ESR1, TTC3, SETDB1, XIAP, AKT1S1, TRIB3, PDPK1, GSK3
Protein Size: 481
Molecular Weight 56 kDa
Gene ID 208
NCBI Accession NM_001626, NP_001617
UniProt P31751
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling

Application Details

Product Details anti-AKT2 Antibody Target Details AKT2 Handling References for anti-AKT2 antibody (ABIN2779323) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 481 AA
Restrictions For Research Use only

Handling

Product Details anti-AKT2 Antibody Target Details AKT2 Application Details References for anti-AKT2 antibody (ABIN2779323) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AKT2 antibody (ABIN2779323)

Product Details anti-AKT2 Antibody Target Details AKT2 Application Details Handling Images back to top
Product cited in:

Tan, Timakhov, Rao, Altomare, Xu, Liu, Gao, Jhanwar, Di Cristofano, Wiest, Knepper, Testa: "A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice." in: Cancer research, Vol. 68, Issue 5, pp. 1296-302, 2008

Images

Product Details anti-AKT2 Antibody Target Details AKT2 Application Details Handling References for anti-AKT2 antibody (ABIN2779323) back to top
Supplier Images
Western Blotting (WB) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) antibody (ABIN2779323) Host: Rabbit Target Name: AKT2 Sample Tissue: Human Fetal Muscle Antibody Dilution...
Western Blotting (WB) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) antibody (ABIN2779323) WB Suggested Anti-AKT2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Posit...
Immunohistochemistry (IHC) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) antibody (ABIN2779323) Rabbit Anti-AKT2 Antibody Formalin Fixed Paraffin Embedded Tissue: Human Thyroid Ti...
Immunohistochemistry (IHC) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) antibody (ABIN2779323) Rabbit Anti-AKT2 Antibody Formalin Fixed Paraffin Embedded Tissue: Human heart Tiss...