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|Antigen||Cyclin A2 (CCNA2) Antibodies|
|Conjugate||This Cyclin A antibody is un-conjugated Alternatives|
Dot Blot (DB), Immunocytochemistry (ICC), Western Blotting (WB)
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Product Details anti-Cyclin A AntibodyTarget Details Cyclin A Application Details Handling Images
|Cross-Reactivity||Human, Mouse (Murine), Rat (Rattus)|
|Cross-Reactivity (Details)||Other species not studied.|
|Purification||Protein G affinity chromatography|
|Immunogen||CCNA2 antibody was raised in mouse using recombinant Human Cyclin A2 (Ccna2)|
Target Details Cyclin AProduct Details anti-Cyclin A Antibody Application Details Handling Images back to top
|Alternative Name||CCNA2 (CCNA2 Antibody Abstract)|
|Background||The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. Synonyms: Monoclonal CCNA2 antibody, Anti-CCNA2 antibody, Cyclin A2 antibody, CCN1 antibody, CCNA antibody.|
|Pathways||PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA|
Application DetailsProduct Details anti-Cyclin A Antibody Target Details Cyclin A Handling Images back to top
WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Cyclin A Antibody Target Details Cyclin A Application Details Images back to top
|Buffer||CCNA2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).|
|Precaution of Use||This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.|
ImagesProduct Details anti-Cyclin A Antibody Target Details Cyclin A Application Details Handling back to top