anti-Human Cyclin D1 antibody for Immunohistochemistry (Frozen Sections)

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • BCL1
  • D11S287E
  • PRAD1
  • U21B31
  • AI327039
  • CycD1
  • Cyl-1
  • bcl-1
  • cD1
  • cb161
  • cycd1
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • ccnd1b
  • prad1
  • ccnd1
  • ccnd1a
  • bcl1
  • d11s287e
  • u21b31
  • CCND1
  • cyclin D1
  • cyclin D1 S homeolog
  • cyclin D1 L homeolog
  • CCND1
  • Ccnd1
  • ccnd1
  • ccnd1.S
  • ccnd1.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
513
274
247
44
38
17
17
16
15
4
4
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Host
Mouse
357
237
15
6
Clonality
Monoclonal
Conjugate
This Cyclin D1 antibody is un-conjugated
31
27
17
13
9
7
7
4
4
4
4
4
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
537
197
157
149
143
122
100
77
47
43
22
8
7
6
3
3
1
1
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Catalog No. ABIN3043639
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
15.5816765 ABIN870487 IHC (fro) IHC (p) Rabbit C-Term Log in to see E16-I 0
15.5816765 ABIN870491 IHC (fro) IHC (p) Rabbit C-Term Log in to see E16-I 0
12.5816765 ABIN2138614 ICC IHC (fro) IHC (p) WB Mouse IgG2a Log in to see CY-D1 0
12.5816765 ABIN1689499 ICC IHC (fro) IHC (p) WB Mouse IgG2a Log in to see CY-D1 0
7 ABIN574432 ELISA FACS ICC IHC IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see CD1-1 0
5.5 ABIN2473139 IHC (fro) FACS IP IHC (p) ELISA WB Mouse IgG1 Log in to see CD1-1 2
4 ABIN1106872 IHC (fro) IF IHC (p) WB Mouse IgG2a Log in to see CY-D1 3
4 ABIN614708 EIA IHC (fro) IF IHC (p) IP WB Mouse IgG1 Log in to see CD1-1 0
4 ABIN1978979 IHC IHC (fro) IHC (p) Rabbit C-Term Log in to see Polyclonal 0
4 ABIN5774051 IHC (fro) IHC (p) Rabbit C-Term Log in to see E16-I 0
1 ABIN1501952 ICC IHC IHC (fro) IHC (p) WB Mouse IgG2a Log in to see CYD1 0
1 ABIN609471 ICC IHC IHC (fro) IHC (p) WB Mouse IgG2a Log in to see 0
1 ABIN119000 EIA FACS IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see CD1-1 0
1 ABIN200701 ELISA FACS IHC IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see 0
1 ABIN2769438 ELISA FACS ICC IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see CD1-1 0
1 ABIN2592484 IHC IHC (fro) IHC (p) Rabbit IgG Log in to see RBT14 0
1 ABIN3199356 IHC (fro) IHC (p) Rabbit C-Term Log in to see Polyclonal 0
1 ABIN640678 IHC (fro) FACS IHC (p) IP ELISA WB Mouse Log in to see 0
1 ABIN643684 IHC (fro) IHC (p) Mouse Log in to see 0
1 ABIN533222 IHC (fro) IF IHC (p) WB Mouse IgG2a Log in to see CY-D1 3

General

Antigen Cyclin D1 (CCND1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(513), (274), (247), (44), (38), (17), (17), (16), (15), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(357), (237), (15), (6)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Cyclin D1 antibody is un-conjugated
(31), (27), (17), (13), (9), (7), (7), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(537), (197), (157), (149), (143), (122), (100), (77), (47), (43), (22), (8), (7), (6), (3), (3), (1), (1)
Pubmed 36 references available
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 antibody (ABIN3043639) Images
Purpose Mouse IgG monoclonal antibody for Cyclin D1, cyclin D1 (CCND1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,mouse,rat. No cross reactivity with other proteins.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Mouse IgG monoclonal antibody for Cyclin D1, cyclin D1 (CCND1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,mouse,rat.
Gene Name: cyclin D1
Protein Name: G1/S-specific cyclin-D1
Purification Ascites
Immunogen Recombinant human cyclin D1 protein.
Clone DCS-6
Isotype IgG2a
Plasmids, Primers & others

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling References for anti-Cyclin D1 antibody (ABIN3043639) Images back to top
Antigen
Alternative Name CCND1 (CCND1 Antibody Abstract)
Background D-type cyclins(cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. CyclinD1(CCND1), also known as BCL1. Expression of cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. CCND1 gene to 11q13. cyclin D1 gene can function as an oncogene. Cyclin D1 expression is regulated by the retinoblastoma protein.

Synonyms: BCL1|U21B31|D11S287|PRAD1|B-CELL LEUKEMIA 1|B-cell CLL/lymphoma 1|G1/S-specific cyclin D1|parathyroid adenomatosis 1|B-cell lymphoma 1 protein|BCL-1 oncogene|PRAD1 oncogene
Gene ID 595, 12443, 58919
UniProt P24385, P25322, P39948
Pathways PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling References for anti-Cyclin D1 antibody (ABIN3043639) Images back to top
Application Notes WB: Concentration: 4 μg/mL, Species: Human, mouse, rat
IHC-P: Concentration: 8 μg/mL, Species: Human, mouse, rat
IHC-F: Concentration: 8 μg/mL, Species: Human, mouse, rat
ICC: Concentration: 1 μg/mL, Species: Human, mouse, rat
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921123 in WB, supported by ABIN921230 in IHC(P), IHC(F) and ICC.

Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details References for anti-Cyclin D1 antibody (ABIN3043639) Images back to top
Format Lyophilized
Reconstitution Add 1 mL of PBS buffer will yield a concentration of 100 μg/mL.
Concentration 100 μg/mL
Buffer Mouse ascites fluid, 1.2 % sodium acetate, 2 mg BSA, with 0.01 mg Sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Cyclin D1 antibody (ABIN3043639)

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling Images back to top
Product cited in:

Yang, Gao, Ma, Teng, Liu, Wei, Lu, Cheng, Hou, Zou: "Fucoidan inhibits lymphangiogenesis by downregulating the expression of VEGFR3 and PROX1 in human lymphatic endothelial cells." in: Oncotarget, Vol. 7, Issue 25, pp. 38025-38035, 2018

Feng, Yan, Zhou, Liang, Liang, Zhao, Dong, Ling: "Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis." in: Oncotarget, Vol. 7, Issue 40, pp. 64575-64588, 2018

Li, Zheng, Ji, Liu, Lv, Yang, Hu, Chen, Zhang, Cao: "Effects of low-intensity ultrasound combined with low-dose carboplatin in an orthotopic hamster model of tongue cancer: A preclinical study." in: Oncology reports, Vol. 39, Issue 4, pp. 1609-1618, 2018

Li, Wang, Zhou, Shuang, Zhao, Chen: "Up-Regulation of Long Noncoding RNA SRA Promotes Cell Growth, Inhibits Cell Apoptosis, and Induces Secretion of Estradiol and Progesterone in Ovarian Granular Cells of Mice." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 2384-2390, 2018

Xiao, Dong, Cheng, Mao, Zong, Wu, Wang, Xie, Wang, Lei, Guo: "LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling." in: International journal of oncology, Vol. 53, Issue 3, pp. 1069-1082, 2018

Ren, Qiu, Lü, Ru, Li, Xiang, Yu, Zhang: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, 2017

Ji, Liu, Zhao, Guo, Xia, Lu, Yin, Xu: "Triptolide inhibits proliferation, differentiation and induces apoptosis of osteoblastic MC3T3‑E1 cells." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 7391-7397, 2017

Yuan, Zheng, Li, Xiang, Gao, Ran, Sun, Huang, Xie, Du, Xiao: "Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2." in: Acta biochimica et biophysica Sinica, Vol. 48, Issue 3, pp. 220-8, 2016

Xu, Gu, Ni, Li, Yu, Li, Liu: "The expression of AEG-1 and Cyclin D1 in human bladder urothelial carcinoma and their clinicopathological significance." in: International journal of clinical and experimental medicine, Vol. 8, Issue 11, pp. 21222-8, 2016

Wang, Wang, Xiong, Chen, Ma, Cai, Gao, Sun, Yang, Pang: "Sirt1 AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a." in: Scientific reports, Vol. 6, pp. 21865, 2016

Fan, Li, Li, Wang, Du, Yang, Zhao, Li: "Silencing of carboxypeptidase E inhibits cell proliferation, tumorigenicity, and metastasis of osteosarcoma cells." in: OncoTargets and therapy, Vol. 9, pp. 2795-803, 2016

Ren, Huang, Xu, Yang, Yang, Hu: "Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells." in: Anti-cancer drugs, Vol. 26, Issue 6, pp. 599-611, 2015

He, Chen, Wang, Zhao, Wan, Wang, Mo: "miR-204-5p promotes the adipogenic differentiation of human adipose-derived mesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/?-catenin signaling." in: International journal of molecular medicine, Vol. 35, Issue 6, pp. 1587-95, 2015

Li, Gao, Chu, Teng, Lv, Yang, Yin: "The synergistic antitumor effects of all-trans retinoic acid and C-phycocyanin on the lung cancer A549 cells in vitro and in vivo." in: European journal of pharmacology, Vol. 749, pp. 107-14, 2015

Gao, Tang, He, Liu, Mao, Ji, Lin, Wu: "Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats." in: Frontiers in pharmacology, Vol. 6, pp. 215, 2015

Zhang, Hu, Liu, Ye, Gui, Zhou, Qi, He, Wang, Wang: "CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment." in: Scientific reports, Vol. 5, pp. 15948, 2015

Zhu, Liu, Li, Liu, Wang, Sun, Xiong, Jiang, Zheng, Hu: "Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility." in: Carcinogenesis, Vol. 35, Issue 8, pp. 1901-10, 2014

Liu, Ma, Wu, Li, Zhang, Han, Wang, Reindl, Wu, Ma: "Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-?B signaling." in: BMC cancer, Vol. 14, pp. 686, 2014

Zhang, Zhao, Huang, Meng, Bian, Li: "Melittin restores PTEN expression by down-regulating HDAC2 in human hepatocelluar carcinoma HepG2 cells." in: PLoS ONE, Vol. 9, Issue 5, pp. e95520, 2014

Liu, Zhu, Xiong, Zheng, Hu, Qiu: "Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5750-61, 2014

Images

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 antibody (ABIN3043639) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Mouse Intestine Tissue
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Human Placenta Tissue
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Rat Intestine Tissue
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Mouse Spleen Tissue