anti-Rat (Rattus) Cyclin D1 antibody for Western Blotting

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • BCL1
  • D11S287E
  • PRAD1
  • U21B31
  • AI327039
  • CycD1
  • Cyl-1
  • bcl-1
  • cD1
  • cb161
  • cycd1
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • ccnd1b
  • prad1
  • ccnd1
  • ccnd1a
  • bcl1
  • d11s287e
  • u21b31
  • CCND1
  • cyclin D1
  • cyclin D1 S homeolog
  • cyclin D1 L homeolog
  • CCND1
  • Ccnd1
  • ccnd1
  • ccnd1.S
  • ccnd1.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
471
234
209
43
18
16
15
4
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Host
Mouse
353
179
6
Clonality
Monoclonal
Conjugate
This Cyclin D1 antibody is un-conjugated
28
25
15
9
7
7
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
487
168
167
112
103
82
74
47
38
24
23
9
8
7
2
1
1
1
1
Options
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Catalog No. ABIN3043639
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
25.715494 ABIN3044355 WB Rabbit IgG AA 219-238, C-Term Log in to see Polyclonal 36
24.215494 ABIN6261145 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 10
22.715494 ABIN5518654 WB Rabbit IgG AA 19-37, N-Term Log in to see Polyclonal 40
19.715494 ABIN1871539 IHC WB Rabbit IgG Log in to see Polyclonal 0
19.715494 ABIN5996938 IF/ICC IHC IP WB Rabbit IgG Log in to see 0
19.715494 ABIN4903416 ICC IHC IP WB Rabbit IgG Log in to see 0
18.751276 ABIN3184144 ELISA IHC WB Rabbit IgG Ser166 Log in to see Polyclonal 0
18.751276 ABIN3182196 ELISA IHC WB Rabbit IgG pThr286 Log in to see Polyclonal 0
18.751276 ABIN3181597 IHC WB Rabbit IgG Log in to see Polyclonal 0
18.215494 ABIN6712231 IHC WB Rabbit AA 250-300 Log in to see Polyclonal 17
16.715494 ABIN3026634 FACS IF IHC (p) WB Mouse IgG2a, kappa Log in to see DCS-6 0
13.715493 ABIN6271254 ELISA ICC IF IHC WB Rabbit IgG pSer90 Log in to see Polyclonal 0
13.715493 ABIN3024574 FACS IF IHC (p) WB Mouse IgG2a, kappa Log in to see SPM587 0
13 ABIN3026636 FACS IF IHC (p) WB Mouse IgG2a, kappa Log in to see DCS-6 0
12.215493 ABIN6261146 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 1
12.035782 ABIN3184143 ELISA WB Rabbit IgG Ser165 Log in to see Polyclonal 0
12.035782 ABIN302101 ELISA FACS ICC IHC (f) IHC (p) IP WB Mouse IgG1 Log in to see CD1-1 2
12.035782 ABIN5650801 IHC WB Atto 700 Rabbit AA 1-100 Log in to see Polyclonal 0
12.035782 ABIN5650807 IHC WB PerCP Rabbit AA 1-100 Log in to see Polyclonal 0
12.035782 ABIN5650800 IHC WB Atto 680 Rabbit AA 1-100 Log in to see Polyclonal 0

General

Antigen Cyclin D1 (CCND1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(471), (234), (209), (43), (18), (16), (15), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(353), (179), (6)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Cyclin D1 antibody is un-conjugated
(28), (25), (15), (9), (7), (7), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(487), (168), (167), (112), (103), (82), (74), (47), (38), (24), (23), (9), (8), (7), (2), (1), (1), (1), (1)
Pubmed 36 references available
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 antibody (ABIN3043639) Images
Purpose Mouse IgG monoclonal antibody for Cyclin D1, cyclin D1 (CCND1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,mouse,rat. No cross reactivity with other proteins.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Mouse IgG monoclonal antibody for Cyclin D1, cyclin D1 (CCND1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,mouse,rat.
Gene Name: cyclin D1
Protein Name: G1/S-specific cyclin-D1
Purification Ascites
Immunogen Recombinant human cyclin D1 protein.
Clone DCS-6
Isotype IgG2a
Plasmids, Primers & others

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling References for anti-Cyclin D1 antibody (ABIN3043639) Images back to top
Antigen
Alternative Name CCND1 (CCND1 Antibody Abstract)
Background D-type cyclins(cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. CyclinD1(CCND1), also known as BCL1. Expression of cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. CCND1 gene to 11q13. cyclin D1 gene can function as an oncogene. Cyclin D1 expression is regulated by the retinoblastoma protein.

Synonyms: BCL1|U21B31|D11S287|PRAD1|B-CELL LEUKEMIA 1|B-cell CLL/lymphoma 1|G1/S-specific cyclin D1|parathyroid adenomatosis 1|B-cell lymphoma 1 protein|BCL-1 oncogene|PRAD1 oncogene
Gene ID 595, 12443, 58919
UniProt P24385, P25322, P39948
Pathways PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling References for anti-Cyclin D1 antibody (ABIN3043639) Images back to top
Application Notes WB: Concentration: 4 μg/mL, Species: Human, mouse, rat
IHC-P: Concentration: 8 μg/mL, Species: Human, mouse, rat
IHC-F: Concentration: 8 μg/mL, Species: Human, mouse, rat
ICC: Concentration: 1 μg/mL, Species: Human, mouse, rat
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921123 in WB, supported by ABIN921230 in IHC(P), IHC(F) and ICC.

Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details References for anti-Cyclin D1 antibody (ABIN3043639) Images back to top
Format Lyophilized
Reconstitution Add 1 mL of PBS buffer will yield a concentration of 100 μg/mL.
Concentration 100 μg/mL
Buffer Mouse ascites fluid, 1.2 % sodium acetate, 2 mg BSA, with 0.01 mg Sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Cyclin D1 antibody (ABIN3043639)

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling Images back to top
Product cited in:

Yang, Gao, Ma, Teng, Liu, Wei, Lu, Cheng, Hou, Zou: "Fucoidan inhibits lymphangiogenesis by downregulating the expression of VEGFR3 and PROX1 in human lymphatic endothelial cells." in: Oncotarget, Vol. 7, Issue 25, pp. 38025-38035, 2018

Feng, Yan, Zhou, Liang, Liang, Zhao, Dong, Ling: "Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis." in: Oncotarget, Vol. 7, Issue 40, pp. 64575-64588, 2018

Li, Zheng, Ji, Liu, Lv, Yang, Hu, Chen, Zhang, Cao: "Effects of low-intensity ultrasound combined with low-dose carboplatin in an orthotopic hamster model of tongue cancer: A preclinical study." in: Oncology reports, Vol. 39, Issue 4, pp. 1609-1618, 2018

Li, Wang, Zhou, Shuang, Zhao, Chen: "Up-Regulation of Long Noncoding RNA SRA Promotes Cell Growth, Inhibits Cell Apoptosis, and Induces Secretion of Estradiol and Progesterone in Ovarian Granular Cells of Mice." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 2384-2390, 2018

Xiao, Dong, Cheng, Mao, Zong, Wu, Wang, Xie, Wang, Lei, Guo: "LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling." in: International journal of oncology, Vol. 53, Issue 3, pp. 1069-1082, 2018

Ren, Qiu, Lü, Ru, Li, Xiang, Yu, Zhang: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, 2017

Ji, Liu, Zhao, Guo, Xia, Lu, Yin, Xu: "Triptolide inhibits proliferation, differentiation and induces apoptosis of osteoblastic MC3T3‑E1 cells." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 7391-7397, 2017

Yuan, Zheng, Li, Xiang, Gao, Ran, Sun, Huang, Xie, Du, Xiao: "Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2." in: Acta biochimica et biophysica Sinica, Vol. 48, Issue 3, pp. 220-8, 2016

Xu, Gu, Ni, Li, Yu, Li, Liu: "The expression of AEG-1 and Cyclin D1 in human bladder urothelial carcinoma and their clinicopathological significance." in: International journal of clinical and experimental medicine, Vol. 8, Issue 11, pp. 21222-8, 2016

Wang, Wang, Xiong, Chen, Ma, Cai, Gao, Sun, Yang, Pang: "Sirt1 AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a." in: Scientific reports, Vol. 6, pp. 21865, 2016

Fan, Li, Li, Wang, Du, Yang, Zhao, Li: "Silencing of carboxypeptidase E inhibits cell proliferation, tumorigenicity, and metastasis of osteosarcoma cells." in: OncoTargets and therapy, Vol. 9, pp. 2795-803, 2016

Ren, Huang, Xu, Yang, Yang, Hu: "Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells." in: Anti-cancer drugs, Vol. 26, Issue 6, pp. 599-611, 2015

He, Chen, Wang, Zhao, Wan, Wang, Mo: "miR-204-5p promotes the adipogenic differentiation of human adipose-derived mesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/?-catenin signaling." in: International journal of molecular medicine, Vol. 35, Issue 6, pp. 1587-95, 2015

Li, Gao, Chu, Teng, Lv, Yang, Yin: "The synergistic antitumor effects of all-trans retinoic acid and C-phycocyanin on the lung cancer A549 cells in vitro and in vivo." in: European journal of pharmacology, Vol. 749, pp. 107-14, 2015

Gao, Tang, He, Liu, Mao, Ji, Lin, Wu: "Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats." in: Frontiers in pharmacology, Vol. 6, pp. 215, 2015

Zhang, Hu, Liu, Ye, Gui, Zhou, Qi, He, Wang, Wang: "CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment." in: Scientific reports, Vol. 5, pp. 15948, 2015

Zhu, Liu, Li, Liu, Wang, Sun, Xiong, Jiang, Zheng, Hu: "Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility." in: Carcinogenesis, Vol. 35, Issue 8, pp. 1901-10, 2014

Liu, Ma, Wu, Li, Zhang, Han, Wang, Reindl, Wu, Ma: "Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-?B signaling." in: BMC cancer, Vol. 14, pp. 686, 2014

Zhang, Zhao, Huang, Meng, Bian, Li: "Melittin restores PTEN expression by down-regulating HDAC2 in human hepatocelluar carcinoma HepG2 cells." in: PLoS ONE, Vol. 9, Issue 5, pp. e95520, 2014

Liu, Zhu, Xiong, Zheng, Hu, Qiu: "Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5750-61, 2014

Images

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 antibody (ABIN3043639) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Mouse Intestine Tissue
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Human Placenta Tissue
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Rat Intestine Tissue
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Mouse Spleen Tissue