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|Antigen||Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This GRIA2 antibody is conjugated to Cy3 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-GRIA2 AntibodyTarget Details GRIA2 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic phosphopeptide derived from human Gria2 around the phosphorylation site of Ser880|
Target Details GRIA2Product Details anti-GRIA2 Antibody Application Details Handling Images back to top
|Alternative Name||Gria2 (GRIA2 Antibody Abstract)|
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG, Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Synonyms: Glutamate receptor 2 PrecursorSer880, Gria2, Glur-2, GluR-B, Glur2, GluR-2, GluR-K2, Glutamate receptor 2, Glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, N-methyl D-aspartate 1, NMDA receptor subunit , AMPA-selective glutamate receptor 2.
Application DetailsProduct Details anti-GRIA2 Antibody Target Details GRIA2 Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-GRIA2 Antibody Target Details GRIA2 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|