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|Antigen||Glycogen Synthase Kinase 3 alpha (GSK3a) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This GSK3 alpha antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
|4 references available|
|Supplier||Log in to see|
Product Details anti-GSK3 alpha AntibodyTarget Details GSK3 alpha Application Details Handling References for anti-GSK3 alpha antibody (ABIN4900770) Images
|Specificity||Detects human, mouse, and rat GSK-3 beta and the closely related GSK-3 alpha .|
|Purification||Immunogen affinity purified|
|Sterility||0.2 μm filtered|
|Immunogen||E. coli-derived recombinant human GSK-3 beta , Accession # P49841|
Target Details GSK3 alphaProduct Details anti-GSK3 alpha Antibody Application Details Handling References for anti-GSK3 alpha antibody (ABIN4900770) Images back to top
|Alternative Name||GSK3A (GSK3a Antibody Abstract)|
|Background||Alternative Names: DKFZp686D0638, EC 2.7.11, EC 184.108.40.206, glycogen synthase kinase 3 alpha, glycogen synthase kinase-3 alpha, GSK3 alpha, GSK-3 alpha, GSK3 beta, GSK3A, GSK3B|
|Pathways||PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process|
Application DetailsProduct Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Handling References for anti-GSK3 alpha antibody (ABIN4900770) Images back to top
Western Blot 0.1 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
Immunocytochemistry 5-15 μg/mL
|Restrictions||For Research Use only|
HandlingProduct Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details References for anti-GSK3 alpha antibody (ABIN4900770) Images back to top
|Reconstitution||Reconstitute at 0.2 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-GSK3 alpha antibody (ABIN4900770)Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details Handling Images back to top
|Product cited in:||
Brethour, Mehrabian, Williams, Wang, Ghodrati, Ehsani, Rubie, Woodgett, Sevalle, Xi, Rogaeva, Schmitt-Ulms: "A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition." in: Scientific reports, Vol. 7, pp. 40313, 2017 Method employed by authors: Immunoprecipitation (IP) (Sample species: Mouse (Murine)).
Lutay, Håkansson, Alaridah, Hallgren, Westergren-Thorsson, Godaly: "Mycobacteria bypass mucosal NF-kB signalling to induce an epithelial anti-inflammatory IL-22 and IL-10 response." in: PLoS ONE, Vol. 9, Issue 1, pp. e86466, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Human).
Lapid, Itkin, DUva, Ovadya, Ludin, Caglio, Kalinkovich, Golan, Porat, Zollo, Lapidot: "GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement." in: The Journal of clinical investigation, Vol. 123, Issue 4, pp. 1705-17, 2013 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
Tang, Arjunan, Lee, Li, Kumar, Hou, Wang, Wardega, Zhang, Dong, Zhang, Zhang, Ding, Fariss, Becker, Lennartsson, Nagai, Cao, Li: "Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation." in: The Journal of experimental medicine, Vol. 207, Issue 4, pp. 867-80, 2010 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Rat (Rattus)).
ImagesProduct Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details Handling References for anti-GSK3 alpha antibody (ABIN4900770) back to top