General
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Antigen
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Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies
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Reactivity
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Human
Alternatives
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Host
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Mouse
Alternatives
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Clonality (Clone)
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Conjugate
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This PDK2 antibody is un-conjugated
Alternatives
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Application
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Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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Supplier
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Log in to see
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Specificity
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This antibody reacts to PDK2.
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Purification
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Protein A chromatography
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Immunogen
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PDK2 antibody was raised against recombinant protein
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Clone
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2G1
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Isotype
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IgG2a
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Plasmids, Primers & others
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Antigen
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Alternative Name
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PDK2 (PDK2 Antibody Abstract)
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Background
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PDK2 belongs to the PDK/BCKDK protein kinase subfamily. PDK2 contributes to the regulation of glucose metabolism by inhibiting the mitochondrial pyruvate dehyrogenase complex by phosphorylating the E1 alpha subunit. PDK2 corresponds to a possibly free or soluble form of pyruvate dehydrogenase kinase that was originally named kinase activator protein.Synonyms: Pyruvate dehydrogenase kinase isoform 2, Pyruvate dehydrogenase lipoamide kinase isozyme 2 mitochondrial
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Gene ID
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5164
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NCBI Accession
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NP_001186828
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UniProt
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Q15119
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Pathways
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PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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Application Notes
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Optimal working dilution should be determined by the investigator.
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Restrictions
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For Research Use only
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Concentration
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0,5 mg/mL
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Buffer
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PBS, pH 7.2
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Handling Advice
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Avoid repeated freezing and thawing.
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Storage
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4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Supplier Images
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