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anti-Mouse (Murine) PIP5K1B Antibodies:
anti-Rat (Rattus) PIP5K1B Antibodies:
anti-Human PIP5K1B Antibodies:
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Human Polyclonal PIP5K1B Primary Antibody for IHC (p), WB - ABIN392594
Qin, Li, Pan, Wu: Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl. in The Journal of biological chemistry 2009
Show all 2 Pubmed References
Human Polyclonal PIP5K1B Primary Antibody for ELISA, WB - ABIN521867
Bayot, Reichman, Lebon, Csaba, Aubry, Sterkers, Husson, Rak, Rustin: Cis-silencing of PIP5K1B evidenced in Friedreich's ataxia patient cells results in cytoskeleton anomalies. in Human molecular genetics 2013
synthesis of PtdIns(4,5)P(2) mediated by PIP5KIbeta is rate limiting for apical but not basolateral endocytosis in polarized kidney cells
The results suggested that PIP5K1A and PIP5K1B may coordinately and/or redundantly function in the maintenance of sperm number and morphology during spermatogenesis.
Phosphatidylinositol 4-phosphate 5-kinase (show PIP4K2C Antibodies) is essential for ROCK-mediated neurite remodeling
PIPKIalpha activity is involved in the actin remodeling that is a prerequisite for efficient phagocytosis
These results indicate that both Arf6 (show ARF6 Antibodies) and PIP5K (show PIKFYVE Antibodies) are involved in integrin-dependent bacterial uptake, and that Arf6 (show ARF6 Antibodies) participates in both activation of PIP5K (show PIKFYVE Antibodies) as well as in other events associated with bacterial uptake.
findings indicate that synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) by the three phosphatidylinositol 4-phosphate 5-kinase (show PIP4K2C Antibodies) (PIP5K (show PIKFYVE Antibodies)) isoforms Ialpha, Ibeta and Igamma is controlled by Rho GTPases
phosphatidylinositol phosphate kinase type I alpha is a negative regulator of FcepsilonRI (show FCER1A Antibodies)-mediated cellular responses and anaphylaxis.
after stimulation of a G protein-coupled receptor (show GPR34 Antibodies), IP(3) is completely derived from a rapidly synthesized discrete pool of PIP(2) synthesized by PIP5KIalpha and PIP5KIbeta
Data indicate that type I phosphatidylinositol 4-phosphate 5-kinase (show PIP4K2C Antibodies) PIP5KIbeta mutants whose dimerization was impaired showed a severe decrease in PI(4,5)P2 production and plasma membrane delocalization.
Knockdown of PIP5K1B in fibroblasts reproduced abnormal actin cytoskeleton remodeling evidenced in Friedreich's ataxia patient cells.
Results identify an isoform-specific PDZ (show INADL Antibodies)-binding motif in PIP5KIbeta, which confers specificity for PIP5KIbeta signaling at the uropod during leukocyte chemotaxis.
findings show that the human type I phosphatidylinositol 4-phosphate 5-kinase (show PIP4K2C Antibodies) isoform beta (PIPKIbeta) has a role in organizing signaling at the cell rear
Syk (show SYK Antibodies)-dependent phosphorylation of PIP5K1B is the dominant modification responsible for the decrease in cellular phosphatidylinositol 4,5-bisphosphate.
Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion (By similarity).
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
, phosphatidylinositol-4-phosphate 5-kinase type-1 beta-like
, phosphatidylinositol 4-phosphate 5-kinase type I alpha
, phosphatidylinositol 4-phosphate 5-kinase type I beta
, phosphatidylinositol 4-phosphate 5-kinase type-1 beta
, phosphatidylinositol-4-phosphate 5-kinase type I alpha
, phosphatidylinositol-4-phosphate 5-kinase type I beta
, phosphatidylinositol-4-phosphate 5-kinase type-1 beta
, ptdIns(4)P-5-kinase 1 beta
, phosphatidylinositol-4-phosphate 5-kinase type-1 alpha
, phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
, phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
, protein STM-7
, type I phosphatidylinositol 4-phosphate 5-kinase beta
, type I phosphatidylinositol-4-phosphate 5-kinase beta
, phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
, phosphatidylinositol-4-phosphate 5-kinase, type 1, beta
, ptdIns(4)P-5-kinase beta