We are preparing the requested document. Please wait, this may take a while...!
|Antigen||Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) Antibodies|
|Conjugate||This PIP5K1C antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|3 references available|
|Supplier||Log in to see|
Product Details anti-PIP5K1C AntibodyTarget Details PIP5K1C Application Details Handling References for anti-PIP5K1C antibody (ABIN360481) Images
|Specificity||This antibody reacts to PIP5KI gamma.|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PIP5K1G.|
Target Details PIP5K1CProduct Details anti-PIP5K1C Antibody Application Details Handling References for anti-PIP5K1C antibody (ABIN360481) Images back to top
|Alternative Name||PIP5K1C (PIP5K1C Antibody Abstract)|
|Background||PIP5K1G is a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes. A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus.Synonyms: KIAA0589, PIP5K1-gamma, PIP5KIgamma, Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma, PtdIns(4)P-5-kinase 1 gamma|
|Gene ID||23396, 9606|
|Pathways||PI3K-Akt Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization, Maintenance of Protein Location, Synaptic Vesicle Exocytosis|
Application DetailsProduct Details anti-PIP5K1C Antibody Target Details PIP5K1C Handling References for anti-PIP5K1C antibody (ABIN360481) Images back to top
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-PIP5K1C Antibody Target Details PIP5K1C Application Details References for anti-PIP5K1C antibody (ABIN360481) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-PIP5K1C antibody (ABIN360481)Product Details anti-PIP5K1C Antibody Target Details PIP5K1C Application Details Handling Images back to top
Ling, Doughman, Firestone, Bunce, Anderson: "Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions." in: Nature, Vol. 420, Issue 6911, pp. 89-93, 2002
Di Paolo, Pellegrini, Letinic, Cestra, Zoncu, Voronov, Chang, Guo, Wenk, De Camilli: "Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin." in: Nature, Vol. 420, Issue 6911, pp. 85-9, 2002
Ishihara, Shibasaki, Kizuki, Wada, Yazaki, Asano, Oka: "Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8741-8, 1998
ImagesProduct Details anti-PIP5K1C Antibody Target Details PIP5K1C Application Details Handling References for anti-PIP5K1C antibody (ABIN360481) back to top