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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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3.2583594 | ABIN2564639 | ELISA WB | Goat | IgG | C-Term | Log in to see | Polyclonal | 0 |
General |
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Antigen | Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) Antibodies |
Epitope | C-Term Alternatives |
Reactivity | Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This PPP2R4 antibody is un-conjugated Alternatives |
Application |
Western Blotting (WB)
Alternatives
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Supplier | Log in to see |
Product Details anti-PPP2R4 AntibodyTarget Details PPP2R4 Application Details Handling Images |
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Blocking Peptide | Blocking peptide for this product available: ABIN982129 |
Sequence | RHFVDEKAVN ENHKDYMFLE CILFITEMKT GPFAEHSNQL WNISAVPSWS |
Predicted Reactivity | Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100% |
Characteristics | This is a rabbit polyclonal antibody against PPP2R4. It was validated on Western Blot. |
Purification | Affinity Purified |
Target Details PPP2R4Product Details anti-PPP2R4 Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | PPP2R4 (PPP2R4 Antibody Abstract) |
Background |
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. Alias Symbols: MGC2184, PP2A, PR53, PTPA Protein Interaction Partner: AMOT, MID1, BHLHB9, SP3, STAT1, IER3, UBC, PRKCB, MAPT, EIF4EBP1, RACGAP1, APP, CAV1, AKT1, MAP2K3, MARK2, ATM, STK26, AURKB, CYLD, PPP1CA, HHV8GK18_gp81, SP1, PPP2CA, MDM2, SET, ARRB2, PIM1, PTEN, PPP2R1A, MYOCD, MYLPF, CCT5, CCT8, CCT2, CCT4, CCT7, CCT3 Protein Size: 358 |
Molecular Weight | 39 kDa |
Gene ID | 5524 |
NCBI Accession | NM_178001, NP_821068 |
UniProt | Q15257 |
Pathways | PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades |
Application DetailsProduct Details anti-PPP2R4 Antibody Target Details PPP2R4 Handling Images back to top |
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Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
Comment |
Antigen size: 358 AA |
Restrictions | For Research Use only |
HandlingProduct Details anti-PPP2R4 Antibody Target Details PPP2R4 Application Details Images back to top |
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Format | Liquid |
Concentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
ImagesProduct Details anti-PPP2R4 Antibody Target Details PPP2R4 Application Details Handling back to top |
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Supplier Images |