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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN108619 | ICC FACS IF IHC (p) IP ELISA WB | Mouse | IgG1 | Log in to see | D45 | 7 | |||
1 | ABIN2629502 | ELISA WB | FITC | Rabbit | IgG | AA 597-837 | Log in to see | Polyclonal | 0 | |
1 | ABIN2629499 | ELISA WB | Biotin | Rabbit | IgG | AA 597-837 | Log in to see | Polyclonal | 0 | |
1 | ABIN2629496 | ELISA WB | Rabbit | IgG | AA 597-837 | Log in to see | Polyclonal | 0 | ||
1 | ABIN1093858 | ELISA WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN1093859 | ELISA WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN2433389 | IHC ELISA | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN2435006 | IHC ELISA | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN2903663 | ELISA IF/ICC IHC WB | Rabbit | AA 597-837 | Log in to see | Polyclonal | 0 |
General |
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Antigen | Transportin 1 (TNPO1) Antibodies |
Reactivity | Mouse (Murine), Rabbit, Human, Monkey Alternatives |
Host | Mouse Alternatives |
Clonality (Clone) | |
Conjugate | This Transportin 1 antibody is un-conjugated Alternatives |
Application |
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
Alternatives
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7 references available |
Supplier | Log in to see |
Product Details anti-Transportin 1 AntibodyTarget Details Transportin 1 Application Details Handling References for anti-Transportin 1 antibody (ABIN108620) Images |
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Purification | Protein A |
Immunogen | Recombinant his tagged transportin1 (Human) |
Clone | D45 |
Isotype | IgG1 |
Target Details Transportin 1Product Details anti-Transportin 1 Antibody Application Details Handling References for anti-Transportin 1 antibody (ABIN108620) Images back to top |
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Antigen | |
Alternative Name | Transportin 1 (TNPO1 Antibody Abstract) |
Background |
Synonyms: Importin beta 2 antibody,IPO 2 antibody,IPO2 antibody,Karyopherin (importin) beta 2antibody,Karyopherin beta 2 antibody,KPN B2 antibody,KPNB 2 antibody,KPNB2 antibody,M9 interacting proteinantibody,M9 region interacting protein antibody,M9 region interaction protein antibody,M9-interacting proteinantibody,MIP 1 antibody,MIP antibody,MIP1 antibody,TNPO 1 antibody,TNPO1 antibody,Transportinantibody,Transportin-1 antibody,Transportin1 antibody,TRN antibody |
Gene ID | 3842, 238799 |
OMIM | 602901 |
UniProt | Q8BFY9 |
Pathways | PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events |
Application DetailsProduct Details anti-Transportin 1 Antibody Target Details Transportin 1 Handling References for anti-Transportin 1 antibody (ABIN108620) Images back to top |
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Application Notes | Optimal antibody dilution should be determined by titration, however as a guideline try, Flow Cyt: Use 1 μg for 106 cells. ICC/IF: Use a concentration of 5 μg/mL. IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. WB: 1:800. Detects a band of approximately 93 kDa (predicted molecular weight: 107 kDa) |
Restrictions | For Research Use only |
HandlingProduct Details anti-Transportin 1 Antibody Target Details Transportin 1 Application Details References for anti-Transportin 1 antibody (ABIN108620) Images back to top |
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Format | Liquid |
Concentration | 1 mg/mL |
Buffer | Purified antibody (from supernatant) containing PBS 0.1 % sodium azide |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | 4 °C |
References for anti-Transportin 1 antibody (ABIN108620)Product Details anti-Transportin 1 Antibody Target Details Transportin 1 Application Details Handling Images back to top |
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Product cited in: |
Yu, Boyce, Wands, Bond, Bertozzi, Kohler: "Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 13, pp. 4834-9, 2012 Brelstaff, Lashley, Holton, Lees, Rossor, Bandopadhyay, Revesz: "Transportin1: a marker of FTLD-FUS." in: Acta neuropathologica, Vol. 122, Issue 5, pp. 591-600, 2011 Gu, Tsuji, Jarboui, Yeo, Sheehy, Hall, Gautier: "Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: novel insights into the regulation of Rev nuclear import." in: Retrovirology, Vol. 8, pp. 17, 2011 Chen, Shao, Cobos, Wang, Gao: "4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone [corrected] induces CRM1-dependent p53 nuclear accumulation in human bronchial epithelial cells." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 116, Issue 1, pp. 206-15, 2010 Janiszewska, De Vito, Le Bitoux, Fusco, Stamenkovic: "Transportin regulates nuclear import of CD44." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30548-57, 2010 Favre, Camps, Arod, Chabert, Rommel, Pasquali: "Chemokine receptor CCR2 undergoes transportin1-dependent nuclear translocation." in: Proteomics, Vol. 8, Issue 21, pp. 4560-76, 2008 |
Background publications |
Siomi, Eder, Kataoka, Wan, Liu, Dreyfuss: "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins." in: The Journal of cell biology, Vol. 138, Issue 6, pp. 1181-92, 1997 |
ImagesProduct Details anti-Transportin 1 Antibody Target Details Transportin 1 Application Details Handling References for anti-Transportin 1 antibody (ABIN108620) back to top |
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Supplier Images |