PKC epsilon Products
(Protein Kinase C, epsilon (PRKCE))
Categories
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008].
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Featured PKC epsilon Categories
PKC epsilon Antibodies
High quality antibodies with extensive validation data.
PKC epsilon ELISA Kits
Reliable ELISA kits for a wide range of species.
PKC epsilon Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PKC epsilon Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
- (2)
- (6)
Cat. No.
ABIN679538
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey
Application
IHC, IF, FACS, IHC (p)
Validations
- (6)
Cat. No.
ABIN1500228
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey
Application
WB, IHC, IF, FACS, IHC (p)
Validations
- (14)
Cat. No.
ABIN1500229
Quantity
100 μL
Datasheet
Datasheet
Recommended PKC epsilon ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN6574158
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958928
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969720
Quantity
96 tests
Datasheet
Datasheet
Recommended PKC epsilon Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5570629
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124653
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3093497
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PKC epsilon products
: "Effect of single and repeated heat stress on chemical signals of heat shock response cascade in the rat's heart." in: Cell stress & chaperones, Vol. 23, Issue 4, pp. 561-570, (2019) (PubMed).: "PKCε inhibits isolation and stemness of side population cells via the suppression of ABCB1 transporter and PI3K/Akt, MAPK/ERK signaling in renal cell carcinoma cell line 769P." in: Cancer letters, Vol. 376, Issue 1, pp. 148-54, (2016) (PubMed).
: "Low expression of PKCα and high expression of KRAS predict poor prognosis in patients with colorectal cancer." in: Oncology letters, Vol. 12, Issue 3, pp. 1655-1660, (2016) (PubMed).
: "Polydatin Attenuates H2O2-Induced Oxidative Stress via PKC Pathway." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5139458, (2016) (PubMed).
: "Adenosine A1 receptor activation modulates human equilibrative nucleoside transporter 1 (hENT1) activity via PKC-mediated phosphorylation of serine-281." in: Cellular signalling, Vol. 27, Issue 5, pp. 1008-18, (2015) (PubMed).
: "Rise and Fall of Kir2.2 Current by TLR4 Signaling in Human Monocytes: PKC-Dependent Trafficking and PI3K-Mediated PIP2 Decrease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3345-54, (2015) (PubMed).
: "Aging causes a slowing in ciliary beat frequency, mediated by PKC?." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 6, pp. L584-9, (2014) (PubMed).
: "Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 34072-85, (2010) (PubMed).
: "Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 20, pp. 8368-73, (2009) (PubMed).
: "Protein kinase Cepsilon makes the life and death decision." in: Cellular signalling, Vol. 19, Issue 8, pp. 1633-42, (2007) (PubMed).
Synonyms and alternative names related to PKC epsilon
protein kinase C epsilon (PRKCE), protein kinase C, epsilon (Prkce), protein kinase C, epsilon a (prkcea), protein kinase C epsilon (prkce), protein kinase C, epsilon (PRKCE), protein kinase C epsilon (Prkce), 5830406C15Rik, fj59b07, nPKC-epsilon, pkc-epsilon, PKCE, Pkce, pkce, PKCepsilon, PKC[e], prkce, PRKCH, R75156, wu:fj59b07Protein level used designations for PKC epsilon
- protein kinase C epsilon type
- nPKC-epsilon
- protein kinase C, epsilon
- protein kinase C epsilon type-like
- PKC-epsilon
- npkc-epsilon
- pkc epsilon
- protein kinase C, eta
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